Name | Number of supported studies | Average coverage | |
---|---|---|---|
basal cell | 6 studies | 26% ± 4% | |
epithelial cell | 5 studies | 36% ± 7% | |
squamous epithelial cell | 3 studies | 46% ± 16% |
Insufficient scRNA-seq data for expression of RHOD at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 3064.54 | 226 / 226 | 98% | 90.54 | 399 / 406 |
prostate | 100% | 911.86 | 244 / 245 | 98% | 55.79 | 490 / 502 |
esophagus | 99% | 3123.19 | 1432 / 1445 | 98% | 125.25 | 179 / 183 |
thymus | 100% | 1195.74 | 651 / 653 | 97% | 81.46 | 587 / 605 |
uterus | 96% | 627.87 | 164 / 170 | 98% | 129.20 | 449 / 459 |
breast | 95% | 693.57 | 436 / 459 | 98% | 88.27 | 1097 / 1118 |
ovary | 94% | 528.15 | 170 / 180 | 99% | 71.80 | 424 / 430 |
pancreas | 100% | 949.13 | 327 / 328 | 93% | 107.95 | 165 / 178 |
kidney | 99% | 842.79 | 88 / 89 | 86% | 33.75 | 772 / 901 |
stomach | 97% | 565.16 | 349 / 359 | 87% | 51.37 | 248 / 286 |
lung | 83% | 430.13 | 480 / 578 | 95% | 76.25 | 1098 / 1155 |
bladder | 86% | 343.29 | 18 / 21 | 91% | 92.85 | 457 / 504 |
intestine | 65% | 284.68 | 626 / 966 | 86% | 52.67 | 454 / 527 |
skin | 95% | 1939.52 | 1712 / 1809 | 36% | 15.44 | 170 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 151.72 | 1 / 1 |
blood vessel | 99% | 1104.55 | 1316 / 1335 | 0% | 0 | 0 / 0 |
heart | 97% | 1326.07 | 832 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 117.52 | 43 / 45 |
eye | 0% | 0 | 0 / 0 | 95% | 44.33 | 76 / 80 |
adipose | 89% | 481.37 | 1069 / 1204 | 0% | 0 | 0 / 0 |
muscle | 84% | 770.14 | 672 / 803 | 0% | 0 | 0 / 0 |
adrenal gland | 7% | 26.24 | 17 / 258 | 11% | 2.87 | 26 / 230 |
brain | 6% | 18.87 | 171 / 2642 | 7% | 2.38 | 48 / 705 |
spleen | 11% | 34.17 | 27 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.88 | 1 / 29 |
peripheral blood | 1% | 5.86 | 11 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030032 | Biological process | lamellipodium assembly |
GO_0007165 | Biological process | signal transduction |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0045785 | Biological process | positive regulation of cell adhesion |
GO_0051017 | Biological process | actin filament bundle assembly |
GO_0030335 | Biological process | positive regulation of cell migration |
GO_0007015 | Biological process | actin filament organization |
GO_0048041 | Biological process | focal adhesion assembly |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0016477 | Biological process | cell migration |
GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
GO_0005886 | Cellular component | plasma membrane |
GO_0005769 | Cellular component | early endosome |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005741 | Cellular component | mitochondrial outer membrane |
GO_0010008 | Cellular component | endosome membrane |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0005525 | Molecular function | GTP binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RHOD |
Protein name | Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1) Ras homolog family member D |
Synonyms | ARHD |
Description | FUNCTION: Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution. . |
Accessions | ENST00000308831.7 ENST00000532559.1 O00212 A0A0B6XJZ9 E9PIG5 |