Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 33 studies | 50% ± 22% | |
| pericyte | 19 studies | 43% ± 24% | |
| oligodendrocyte | 16 studies | 69% ± 19% | |
| oligodendrocyte precursor cell | 16 studies | 69% ± 23% | |
| fibroblast | 16 studies | 47% ± 16% | |
| astrocyte | 14 studies | 32% ± 14% | |
| smooth muscle cell | 13 studies | 45% ± 20% | |
| glutamatergic neuron | 11 studies | 48% ± 26% | |
| GABAergic neuron | 10 studies | 53% ± 23% | |
| adipocyte | 10 studies | 61% ± 21% | |
| endothelial cell of artery | 8 studies | 34% ± 22% | |
| neuron | 7 studies | 44% ± 26% | |
| type I pneumocyte | 7 studies | 59% ± 25% | |
| interneuron | 6 studies | 53% ± 18% | |
| mesothelial cell | 6 studies | 54% ± 22% | |
| vein endothelial cell | 6 studies | 51% ± 27% | |
| endothelial cell of lymphatic vessel | 6 studies | 33% ± 7% | |
| epithelial cell | 5 studies | 36% ± 9% | |
| microglial cell | 5 studies | 42% ± 15% | |
| retina horizontal cell | 5 studies | 55% ± 17% | |
| capillary endothelial cell | 5 studies | 39% ± 17% | |
| type II pneumocyte | 5 studies | 31% ± 8% | |
| granule cell | 4 studies | 34% ± 13% | |
| macrophage | 4 studies | 28% ± 12% | |
| Mueller cell | 4 studies | 40% ± 11% | |
| retinal rod cell | 4 studies | 21% ± 4% | |
| endothelial cell of vascular tree | 4 studies | 57% ± 27% | |
| myofibroblast cell | 4 studies | 29% ± 9% | |
| club cell | 4 studies | 29% ± 6% | |
| cholangiocyte | 3 studies | 49% ± 12% | |
| endothelial cell of sinusoid | 3 studies | 36% ± 16% | |
| hepatic stellate cell | 3 studies | 58% ± 14% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 71% ± 7% | |
| GABAergic interneuron | 3 studies | 49% ± 6% | |
| glial cell | 3 studies | 39% ± 10% | |
| precursor B cell | 3 studies | 32% ± 10% | |
| amacrine cell | 3 studies | 22% ± 1% | |
| GABAergic amacrine cell | 3 studies | 27% ± 4% | |
| retinal ganglion cell | 3 studies | 39% ± 5% | |
| hepatocyte | 3 studies | 57% ± 19% | |
| retinal pigment epithelial cell | 3 studies | 39% ± 9% | |
| ependymal cell | 3 studies | 40% ± 4% | |
| basal cell | 3 studies | 32% ± 10% | |
| kidney distal convoluted tubule epithelial cell | 3 studies | 61% ± 30% | |
| mucus secreting cell | 3 studies | 27% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 3534.26 | 2625 / 2642 | 100% | 27.50 | 702 / 705 |
| thymus | 100% | 7806.51 | 652 / 653 | 98% | 21.02 | 593 / 605 |
| breast | 100% | 7164.26 | 459 / 459 | 98% | 32.55 | 1094 / 1118 |
| stomach | 99% | 2821.93 | 356 / 359 | 91% | 10.35 | 259 / 286 |
| intestine | 99% | 3252.14 | 953 / 966 | 90% | 9.47 | 472 / 527 |
| esophagus | 93% | 2877.66 | 1345 / 1445 | 95% | 12.30 | 174 / 183 |
| lung | 100% | 5263.10 | 578 / 578 | 86% | 8.77 | 994 / 1155 |
| kidney | 100% | 3604.78 | 89 / 89 | 85% | 15.13 | 769 / 901 |
| prostate | 99% | 2782.56 | 243 / 245 | 82% | 6.07 | 414 / 502 |
| ovary | 100% | 7447.01 | 180 / 180 | 80% | 7.27 | 343 / 430 |
| skin | 100% | 4628.94 | 1804 / 1809 | 73% | 7.36 | 343 / 472 |
| pancreas | 74% | 1023.92 | 243 / 328 | 96% | 12.83 | 171 / 178 |
| bladder | 100% | 2969.29 | 21 / 21 | 69% | 6.46 | 350 / 504 |
| uterus | 100% | 4498.92 | 170 / 170 | 68% | 7.27 | 310 / 459 |
| adrenal gland | 97% | 2474.48 | 249 / 258 | 63% | 5.29 | 146 / 230 |
| liver | 85% | 1335.30 | 192 / 226 | 62% | 5.14 | 253 / 406 |
| adipose | 100% | 6991.76 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 7372.37 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 99% | 3028.98 | 238 / 241 | 0% | 0 | 0 / 0 |
| heart | 97% | 2346.29 | 832 / 861 | 0% | 0 | 0 / 0 |
| muscle | 79% | 1232.31 | 635 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 78% | 7.15 | 62 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 4.44 | 27 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 2.28 | 8 / 29 |
| peripheral blood | 4% | 78.69 | 40 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006939 | Biological process | smooth muscle contraction |
| GO_0030198 | Biological process | extracellular matrix organization |
| GO_0001764 | Biological process | neuron migration |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0036438 | Biological process | maintenance of lens transparency |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_1901988 | Biological process | negative regulation of cell cycle phase transition |
| GO_0050808 | Biological process | synapse organization |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0007411 | Biological process | axon guidance |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0016020 | Cellular component | membrane |
| GO_0005769 | Cellular component | early endosome |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0045202 | Cellular component | synapse |
| GO_0030426 | Cellular component | growth cone |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0005634 | Cellular component | nucleus |
| GO_0008134 | Molecular function | transcription factor binding |
| GO_0001540 | Molecular function | amyloid-beta binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | APBB2 |
| Protein name | Amyloid beta protein-binding family B member 2 isoform 1 Amyloid beta protein-binding family B member 2 isoform 2 APBB2 protein Amyloid beta precursor protein binding family B member 2 Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1) Amyloid beta (A4) protein-binding, family B, member 2 (Fe65-like), isoform CRA_c (Amyloid beta precursor protein binding family B member 2) |
| Synonyms | FE65L FE65L1 hCG_33089 |
| Description | FUNCTION: Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (By similarity). Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning (By similarity). Activates transcription of APP . . |
| Accessions | D6RGD4 ENST00000503503.5 ENST00000504305.5 [Q92870-3] ENST00000514920.5 H0YAJ5 ENST00000503264.5 ENST00000510925.5 H0Y9U9 ENST00000509446.5 ENST00000295974.12 [Q92870-1] ENST00000510670.5 H0Y943 ENST00000512510.5 ENST00000508707.5 D6RDY3 ENST00000508676.5 ENST00000513516.5 ENST00000513493.1 D6RB00 D6RB55 A0A0S2Z3A2 D6RAJ4 ENST00000513140.5 [Q92870-2] Q92870 A0A1D5RMR3 D6RD19 G5E9Y1 ENST00000502841.5 [Q92870-3] A0A0S2Z3A0 H0YA92 Q5I0G1 ENST00000506352.5 ENST00000513611.5 ENST00000508593.6 [Q92870-4] D6RAE0 |