PTPN23 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	21% ± 5%	Explore
glutamatergic neuron	3 studies	31% ± 4%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	22% ± 3%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5026.70	1445 / 1445	100%	66.14	183 / 183
prostate	100%	6287.88	245 / 245	100%	46.04	502 / 502
skin	100%	6727.54	1809 / 1809	100%	76.96	472 / 472
thymus	100%	8393.40	653 / 653	100%	47.26	605 / 605
intestine	100%	5222.37	966 / 966	100%	46.94	526 / 527
uterus	100%	6779.56	170 / 170	100%	38.76	458 / 459
ovary	100%	6728.56	180 / 180	100%	73.39	429 / 430
stomach	100%	4082.94	359 / 359	100%	51.22	285 / 286
pancreas	100%	3674.57	328 / 328	99%	39.42	177 / 178
breast	100%	5479.24	459 / 459	99%	44.64	1111 / 1118
brain	100%	4409.18	2629 / 2642	100%	61.25	703 / 705
bladder	100%	5676.24	21 / 21	99%	42.89	499 / 504
kidney	100%	5240.15	89 / 89	98%	30.67	887 / 901
lung	100%	5868.09	578 / 578	98%	40.20	1136 / 1155
adrenal gland	100%	6279.93	258 / 258	98%	41.58	226 / 230
liver	100%	2820.51	226 / 226	97%	25.44	393 / 406
adipose	100%	5308.24	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	66.88	80 / 80
lymph node	0%	0	0 / 0	100%	32.12	29 / 29
muscle	100%	4954.28	803 / 803	0%	0	0 / 0
spleen	100%	6754.21	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	38.19	45 / 45
ureter	0%	0	0 / 0	100%	27.37	1 / 1
blood vessel	100%	4977.08	1334 / 1335	0%	0	0 / 0
heart	99%	2937.76	850 / 861	0%	0	0 / 0
peripheral blood	94%	2688.01	874 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0060271	Biological process	cilium assembly
GO_2000643	Biological process	positive regulation of early endosome to late endosome transport
GO_1903387	Biological process	positive regulation of homophilic cell adhesion
GO_0043162	Biological process	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_1903393	Biological process	positive regulation of adherens junction organization
GO_0032456	Biological process	endocytic recycling
GO_0061357	Biological process	positive regulation of Wnt protein secretion
GO_0010633	Biological process	negative regulation of epithelial cell migration
GO_0045022	Biological process	early endosome to late endosome transport
GO_0043328	Biological process	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0005769	Cellular component	early endosome
GO_0070062	Cellular component	extracellular exosome
GO_0005634	Cellular component	nucleus
GO_0005654	Cellular component	nucleoplasm
GO_0016604	Cellular component	nuclear body
GO_0005737	Cellular component	cytoplasm
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0036064	Cellular component	ciliary basal body
GO_0005768	Cellular component	endosome
GO_0019901	Molecular function	protein kinase binding
GO_0005515	Molecular function	protein binding
GO_0004725	Molecular function	protein tyrosine phosphatase activity

Gene name	PTPN23
Protein name	Protein tyrosine phosphatase non-receptor type 23 Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14)
Synonyms	KIAA1471
Description	FUNCTION: Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes . May act as a negative regulator of Ras-mediated mitogenic activity . Plays a role in ciliogenesis . .
Accessions	ENST00000265562.5 R4GMM7 C9JD91 Q9H3S7 ENST00000602307.5 ENST00000456221.5

PTPN23 report