Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 13 studies | 54% ± 24% | |
astrocyte | 13 studies | 36% ± 15% | |
oligodendrocyte | 13 studies | 35% ± 14% | |
ciliated cell | 12 studies | 29% ± 10% | |
GABAergic neuron | 11 studies | 45% ± 22% | |
endothelial cell | 11 studies | 36% ± 18% | |
oligodendrocyte precursor cell | 11 studies | 32% ± 13% | |
adipocyte | 9 studies | 46% ± 10% | |
neuron | 8 studies | 46% ± 17% | |
epithelial cell | 7 studies | 28% ± 9% | |
interneuron | 6 studies | 59% ± 19% | |
retina horizontal cell | 6 studies | 20% ± 5% | |
endothelial cell of lymphatic vessel | 6 studies | 30% ± 13% | |
retinal ganglion cell | 5 studies | 33% ± 12% | |
granule cell | 4 studies | 41% ± 2% | |
fibroblast | 4 studies | 22% ± 3% | |
pancreatic A cell | 3 studies | 47% ± 23% | |
GABAergic interneuron | 3 studies | 48% ± 10% | |
club cell | 3 studies | 18% ± 1% | |
amacrine cell | 3 studies | 21% ± 4% | |
GABAergic amacrine cell | 3 studies | 23% ± 5% | |
abnormal cell | 3 studies | 27% ± 13% | |
ependymal cell | 3 studies | 35% ± 21% | |
enteroendocrine cell | 3 studies | 27% ± 8% | |
type I pneumocyte | 3 studies | 22% ± 5% | |
goblet cell | 3 studies | 39% ± 28% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 16083.41 | 2642 / 2642 | 99% | 157.82 | 701 / 705 |
prostate | 100% | 6149.05 | 245 / 245 | 99% | 61.56 | 499 / 502 |
intestine | 100% | 5433.86 | 964 / 966 | 98% | 84.72 | 515 / 527 |
breast | 99% | 5684.05 | 456 / 459 | 98% | 73.91 | 1095 / 1118 |
thymus | 100% | 6473.55 | 652 / 653 | 97% | 62.20 | 587 / 605 |
esophagus | 100% | 5053.43 | 1444 / 1445 | 97% | 60.78 | 177 / 183 |
stomach | 99% | 4165.60 | 357 / 359 | 97% | 92.84 | 277 / 286 |
ovary | 100% | 4966.89 | 180 / 180 | 95% | 41.89 | 410 / 430 |
pancreas | 94% | 2835.75 | 307 / 328 | 98% | 62.15 | 175 / 178 |
bladder | 100% | 4680.81 | 21 / 21 | 92% | 47.98 | 462 / 504 |
lung | 96% | 2769.91 | 553 / 578 | 94% | 42.95 | 1087 / 1155 |
uterus | 99% | 4601.31 | 169 / 170 | 88% | 36.14 | 405 / 459 |
kidney | 93% | 2811.30 | 83 / 89 | 82% | 29.59 | 735 / 901 |
skin | 94% | 2582.50 | 1706 / 1809 | 76% | 39.12 | 361 / 472 |
adrenal gland | 84% | 2294.63 | 216 / 258 | 77% | 44.36 | 178 / 230 |
liver | 53% | 1057.91 | 119 / 226 | 60% | 18.44 | 245 / 406 |
blood vessel | 100% | 6949.87 | 1335 / 1335 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 23.76 | 1 / 1 |
adipose | 99% | 6239.51 | 1196 / 1204 | 0% | 0 | 0 / 0 |
muscle | 95% | 3625.08 | 759 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 29.92 | 72 / 80 |
heart | 81% | 2118.04 | 697 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 80% | 24.27 | 36 / 45 |
lymph node | 0% | 0 | 0 / 0 | 24% | 5.19 | 7 / 29 |
spleen | 20% | 331.95 | 47 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 19% | 488.33 | 175 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006890 | Biological process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
GO_0006897 | Biological process | endocytosis |
GO_0048812 | Biological process | neuron projection morphogenesis |
GO_0045332 | Biological process | phospholipid translocation |
GO_1903542 | Biological process | negative regulation of exosomal secretion |
GO_2001135 | Biological process | regulation of endocytic recycling |
GO_1905279 | Biological process | regulation of retrograde transport, endosome to Golgi |
GO_0031902 | Cellular component | late endosome membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0055037 | Cellular component | recycling endosome |
GO_0005769 | Cellular component | early endosome |
GO_0031901 | Cellular component | early endosome membrane |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0032588 | Cellular component | trans-Golgi network membrane |
GO_0005770 | Cellular component | late endosome |
GO_0005768 | Cellular component | endosome |
GO_0140326 | Molecular function | ATPase-coupled intramembrane lipid transporter activity |
GO_0000287 | Molecular function | magnesium ion binding |
GO_0002020 | Molecular function | protease binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | ATP9A |
Protein name | ATP9A protein Probable phospholipid-transporting ATPase IIA (EC 7.6.2.1) (ATPase class II type 9A) Phospholipid-transporting ATPase (EC 7.6.2.1) |
Synonyms | KIAA0611 ATPIIA |
Description | FUNCTION: Plays a role in regulating membrane trafficking of cargo proteins, namely endosome to plasma membrane recycling, probably acting through RAB5 and RAB11 activation . Also involved in endosome to trans-Golgi network retrograde transport . In complex with MON2 and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS, a transporter of Wnt morphogens in developing tissues. Participates in the formation of endosomal carriers that direct WLS trafficking back to Golgi, away from lysosomal degradation . Appears to be implicated in intercellular communication by negatively regulating the release of exosomes . The flippase activity towards membrane lipids and its role in membrane asymmetry remains to be proved . Required for the maintenance of neurite morphology and synaptic transmission (By similarity). . |
Accessions | ENST00000311637.9 O75110 Q96B35 ENST00000338821.6 [O75110-1] A0A0A0MR22 Q2NLD0 |