RAP1GAP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1903697Biological processnegative regulation of microvillus assembly
GO_0043547Biological processpositive regulation of GTPase activity
GO_0007165Biological processsignal transduction
GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_0002250Biological processadaptive immune response
GO_1990792Biological processcellular response to glial cell derived neurotrophic factor
GO_0045665Biological processnegative regulation of neuron differentiation
GO_0043087Biological processregulation of GTPase activity
GO_1904442Biological processnegative regulation of thyroid gland epithelial cell proliferation
GO_0016020Cellular componentmembrane
GO_0005769Cellular componentearly endosome
GO_0043025Cellular componentneuronal cell body
GO_0030425Cellular componentdendrite
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0030424Cellular componentaxon
GO_0042803Molecular functionprotein homodimerization activity
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAP1GAP
Protein nameRAP1 GTPase activating protein (RAP1, GTPase activating protein 1, isoform CRA_e)
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)
RAP1GAP protein
RAP1 GTPase activating protein
SynonymshCG_37586
KIAA0474
RAP1GA1
DescriptionFUNCTION: GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. .

AccessionsF2Z357
ENST00000542643.6 [P47736-2]
ENST00000374765.9 [P47736-1]
A0A0B6XK13
ENST00000495204.5 [P47736-4]
J3KPC5
Q49AP2
ENST00000317967.11
X6R8W7
Q5T3T0
ENST00000374763.6
ENST00000447293.5
ENST00000471600.6
P47736
Q5T3T1
ENST00000374761.6