HAS3 | OmnibusX

Name	Number of supported studies	Average coverage
basal cell	4 studies	17% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of HAS3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	1830.10	21 / 21	81%	72.78	410 / 504
uterus	96%	248.22	163 / 170	64%	48.13	292 / 459
lung	85%	630.98	492 / 578	74%	70.03	851 / 1155
thymus	100%	1241.10	650 / 653	59%	10.72	354 / 605
esophagus	77%	2114.20	1116 / 1445	72%	66.17	132 / 183
intestine	78%	338.07	752 / 966	53%	10.57	277 / 527
stomach	74%	721.56	267 / 359	42%	8.14	120 / 286
prostate	96%	715.93	236 / 245	9%	1.42	46 / 502
breast	86%	1550.46	396 / 459	17%	3.07	191 / 1118
ovary	97%	266.08	175 / 180	5%	0.47	20 / 430
ureter	0%	0	0 / 0	100%	67.68	1 / 1
tonsil	0%	0	0 / 0	89%	76.30	40 / 45
pancreas	47%	99.62	154 / 328	42%	15.19	74 / 178
skin	76%	974.13	1374 / 1809	10%	2.13	48 / 472
spleen	80%	143.50	194 / 241	0%	0	0 / 0
adipose	67%	145.35	811 / 1204	0%	0	0 / 0
kidney	60%	161.65	53 / 89	8%	1.19	69 / 901
brain	54%	128.92	1418 / 2642	7%	0.89	48 / 705
liver	45%	94.85	102 / 226	3%	0.52	12 / 406
blood vessel	39%	70.16	520 / 1335	0%	0	0 / 0
adrenal gland	31%	47.20	80 / 258	1%	0.37	3 / 230
muscle	18%	30.26	143 / 803	0%	0	0 / 0
heart	14%	22.67	121 / 861	0%	0	0 / 0
peripheral blood	1%	4.01	11 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0005975	Biological process	carbohydrate metabolic process
GO_0030213	Biological process	hyaluronan biosynthetic process
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_1900106	Biological process	positive regulation of hyaluranon cable assembly
GO_0045226	Biological process	extracellular polysaccharide biosynthetic process
GO_0085029	Biological process	extracellular matrix assembly
GO_0036117	Cellular component	hyaluranon cable
GO_0000139	Cellular component	Golgi membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0005769	Cellular component	early endosome
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005634	Cellular component	nucleus
GO_0050501	Molecular function	hyaluronan synthase activity
GO_0005515	Molecular function	protein binding
GO_0042802	Molecular function	identical protein binding

Gene name	HAS3
Protein name	Hyaluronan synthase 3 (EC 2.4.1.212) (Hyaluronate synthase 3) (Hyaluronic acid synthase 3) (HA synthase 3) Hyaluronan synthase 3 variant 1 (Hyaluronan synthase 3 variant 2) hyaluronan synthase (EC 2.4.1.212)
Synonyms
Description	FUNCTION: Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis. .
Accessions	Q96RV2 ENST00000569188.6 [O00219-1] O00219 H3BRH5 C0KZD9 ENST00000219322.7 [O00219-2] ENST00000566118.5 ENST00000306560.1 [O00219-1]

HAS3 report