Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 31% ± 15% | |
astrocyte | 12 studies | 33% ± 15% | |
macrophage | 12 studies | 31% ± 14% | |
glutamatergic neuron | 11 studies | 46% ± 26% | |
GABAergic neuron | 10 studies | 40% ± 24% | |
oligodendrocyte precursor cell | 10 studies | 32% ± 14% | |
microglial cell | 9 studies | 31% ± 9% | |
oligodendrocyte | 9 studies | 27% ± 10% | |
myeloid cell | 8 studies | 25% ± 10% | |
epithelial cell | 7 studies | 31% ± 16% | |
dendritic cell | 7 studies | 29% ± 7% | |
fibroblast | 7 studies | 25% ± 10% | |
neuron | 6 studies | 36% ± 14% | |
interneuron | 6 studies | 46% ± 23% | |
retinal cone cell | 6 studies | 27% ± 10% | |
adipocyte | 6 studies | 26% ± 3% | |
ciliated cell | 5 studies | 23% ± 7% | |
endothelial cell of lymphatic vessel | 5 studies | 25% ± 7% | |
pericyte | 5 studies | 27% ± 11% | |
smooth muscle cell | 5 studies | 21% ± 2% | |
type I pneumocyte | 5 studies | 32% ± 10% | |
type II pneumocyte | 5 studies | 21% ± 7% | |
basal cell | 5 studies | 27% ± 19% | |
natural killer cell | 4 studies | 20% ± 3% | |
granule cell | 4 studies | 30% ± 8% | |
mast cell | 4 studies | 22% ± 6% | |
club cell | 4 studies | 22% ± 7% | |
monocyte | 4 studies | 28% ± 7% | |
hematopoietic precursor cell | 3 studies | 24% ± 7% | |
GABAergic interneuron | 3 studies | 34% ± 3% | |
retinal ganglion cell | 3 studies | 26% ± 8% | |
B cell | 3 studies | 20% ± 5% | |
ependymal cell | 3 studies | 30% ± 14% | |
T cell | 3 studies | 17% ± 1% | |
alveolar macrophage | 3 studies | 35% ± 9% | |
lymphocyte | 3 studies | 30% ± 9% | |
transit amplifying cell | 3 studies | 40% ± 28% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 6253.55 | 1445 / 1445 | 100% | 22.84 | 183 / 183 |
pancreas | 100% | 8541.85 | 328 / 328 | 100% | 13.86 | 178 / 178 |
prostate | 100% | 5276.22 | 245 / 245 | 100% | 15.01 | 502 / 502 |
thymus | 100% | 7121.11 | 653 / 653 | 100% | 21.77 | 605 / 605 |
skin | 100% | 7793.69 | 1809 / 1809 | 100% | 24.51 | 471 / 472 |
breast | 100% | 6011.44 | 459 / 459 | 100% | 23.91 | 1114 / 1118 |
intestine | 100% | 5797.29 | 966 / 966 | 100% | 16.19 | 525 / 527 |
uterus | 100% | 5386.52 | 170 / 170 | 100% | 14.83 | 457 / 459 |
brain | 100% | 7549.72 | 2631 / 2642 | 100% | 22.74 | 704 / 705 |
bladder | 100% | 5291.43 | 21 / 21 | 99% | 14.54 | 501 / 504 |
stomach | 100% | 4955.44 | 359 / 359 | 99% | 17.40 | 284 / 286 |
lung | 100% | 7808.54 | 578 / 578 | 99% | 17.03 | 1146 / 1155 |
kidney | 100% | 4941.21 | 89 / 89 | 99% | 14.29 | 892 / 901 |
adrenal gland | 100% | 6252.84 | 258 / 258 | 99% | 14.71 | 227 / 230 |
liver | 100% | 3359.26 | 226 / 226 | 99% | 10.39 | 400 / 406 |
ovary | 100% | 5052.49 | 180 / 180 | 96% | 12.38 | 413 / 430 |
adipose | 100% | 5832.29 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 24.44 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 26.34 | 29 / 29 |
muscle | 100% | 6122.96 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 8082.54 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 19.85 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.79 | 1 / 1 |
blood vessel | 100% | 4910.30 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 2966.83 | 826 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 92% | 6745.77 | 858 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1905337 | Biological process | positive regulation of aggrephagy |
GO_0006890 | Biological process | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
GO_2000479 | Biological process | regulation of cAMP-dependent protein kinase activity |
GO_0042297 | Biological process | vocal learning |
GO_0000132 | Biological process | establishment of mitotic spindle orientation |
GO_1904504 | Biological process | positive regulation of lipophagy |
GO_0031648 | Biological process | protein destabilization |
GO_0043666 | Biological process | regulation of phosphoprotein phosphatase activity |
GO_0031587 | Biological process | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity |
GO_0007030 | Biological process | Golgi organization |
GO_0045724 | Biological process | positive regulation of cilium assembly |
GO_1905289 | Biological process | regulation of CAMKK-AMPK signaling cascade |
GO_1901526 | Biological process | positive regulation of mitophagy |
GO_0006915 | Biological process | apoptotic process |
GO_2001237 | Biological process | negative regulation of extrinsic apoptotic signaling pathway |
GO_0043065 | Biological process | positive regulation of apoptotic process |
GO_0047496 | Biological process | vesicle transport along microtubule |
GO_0099111 | Biological process | microtubule-based transport |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005769 | Cellular component | early endosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005634 | Cellular component | nucleus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0030425 | Cellular component | dendrite |
GO_0005814 | Cellular component | centriole |
GO_0016234 | Cellular component | inclusion body |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0099524 | Cellular component | postsynaptic cytosol |
GO_0005770 | Cellular component | late endosome |
GO_0005776 | Cellular component | autophagosome |
GO_0005737 | Cellular component | cytoplasm |
GO_0099523 | Cellular component | presynaptic cytosol |
GO_0030424 | Cellular component | axon |
GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
GO_0048487 | Molecular function | beta-tubulin binding |
GO_0034452 | Molecular function | dynactin binding |
GO_0019900 | Molecular function | kinase binding |
GO_0031072 | Molecular function | heat shock protein binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0002039 | Molecular function | p53 binding |
GO_0005522 | Molecular function | profilin binding |
GO_0044325 | Molecular function | transmembrane transporter binding |
GO_0045505 | Molecular function | dynein intermediate chain binding |
GO_0005515 | Molecular function | protein binding |
Gene name | HTT |
Protein name | Huntingtin Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment] Huntingtin isoform A |
Synonyms | HD IT15 |
Description | FUNCTION: [Huntingtin]: May play a role in microtubule-mediated transport or vesicle function.; FUNCTION: [Huntingtin, myristoylated N-terminal fragment]: Promotes the formation of autophagic vesicles. . FUNCTION: May play a role in microtubule-mediated transport or vesicle function. . FUNCTION: May play a role in microtubule-mediated transport or vesicle function. . FUNCTION: May play a role in microtubule-mediated transport or vesicle function. . FUNCTION: May play a role in microtubule-mediated transport or vesicle function. . |
Accessions | ENST00000680239.1 ENST00000680360.1 X5DPA1 A0A7P0TA78 ENST00000650595.1 ENST00000681528.1 A0A7P0TAN5 ENST00000649131.1 ENST00000650588.1 H0YA07 A0A3B3ISR3 P42858 ENST00000680956.1 ENST00000355072.11 A0A7P0TAC5 ENST00000509618.1 A0A3B3IU25 A0A7P0Z417 |