Name | Number of supported studies | Average coverage | |
---|---|---|---|
mast cell | 11 studies | 33% ± 14% | |
glutamatergic neuron | 8 studies | 45% ± 25% | |
endothelial cell | 7 studies | 28% ± 9% | |
GABAergic neuron | 5 studies | 43% ± 20% | |
epithelial cell | 4 studies | 20% ± 3% | |
ciliated cell | 4 studies | 20% ± 5% | |
astrocyte | 4 studies | 30% ± 8% | |
interneuron | 4 studies | 44% ± 24% | |
oligodendrocyte | 4 studies | 26% ± 7% | |
neuron | 3 studies | 23% ± 9% | |
oligodendrocyte precursor cell | 3 studies | 28% ± 6% | |
granule cell | 3 studies | 38% ± 14% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 8 studies | 37% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1656.65 | 1445 / 1445 | 100% | 11.73 | 183 / 183 |
lung | 100% | 2174.67 | 578 / 578 | 100% | 10.03 | 1155 / 1155 |
brain | 100% | 5986.48 | 2640 / 2642 | 100% | 14.52 | 704 / 705 |
breast | 100% | 2086.51 | 459 / 459 | 100% | 11.30 | 1113 / 1118 |
prostate | 100% | 1981.42 | 245 / 245 | 99% | 7.99 | 498 / 502 |
uterus | 100% | 2208.27 | 170 / 170 | 99% | 8.13 | 454 / 459 |
skin | 100% | 2367.31 | 1809 / 1809 | 99% | 12.67 | 466 / 472 |
intestine | 100% | 1816.57 | 966 / 966 | 99% | 7.31 | 520 / 527 |
stomach | 100% | 1592.02 | 359 / 359 | 98% | 8.01 | 281 / 286 |
ovary | 100% | 1824.67 | 180 / 180 | 98% | 6.76 | 422 / 430 |
liver | 100% | 2188.20 | 226 / 226 | 98% | 8.64 | 398 / 406 |
thymus | 100% | 2164.96 | 653 / 653 | 98% | 7.26 | 593 / 605 |
kidney | 100% | 1992.06 | 89 / 89 | 98% | 9.21 | 883 / 901 |
bladder | 100% | 1869.52 | 21 / 21 | 98% | 6.99 | 492 / 504 |
pancreas | 98% | 976.91 | 323 / 328 | 99% | 8.83 | 176 / 178 |
adrenal gland | 100% | 1521.00 | 258 / 258 | 93% | 7.48 | 213 / 230 |
adipose | 100% | 2122.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 2485.01 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1656.07 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 7.45 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.49 | 1 / 1 |
blood vessel | 100% | 1828.35 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 100% | 2593.27 | 859 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 8.23 | 75 / 80 |
lymph node | 0% | 0 | 0 / 0 | 83% | 3.84 | 24 / 29 |
peripheral blood | 43% | 420.32 | 404 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051260 | Biological process | protein homooligomerization |
GO_0051036 | Biological process | regulation of endosome size |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0007041 | Biological process | lysosomal transport |
GO_0035022 | Biological process | positive regulation of Rac protein signal transduction |
GO_0007528 | Biological process | neuromuscular junction development |
GO_0045860 | Biological process | positive regulation of protein kinase activity |
GO_0048812 | Biological process | neuron projection morphogenesis |
GO_0016197 | Biological process | endosomal transport |
GO_0043087 | Biological process | regulation of GTPase activity |
GO_0007032 | Biological process | endosome organization |
GO_0007626 | Biological process | locomotory behavior |
GO_0001662 | Biological process | behavioral fear response |
GO_0008104 | Biological process | protein localization |
GO_0006979 | Biological process | response to oxidative stress |
GO_0001881 | Biological process | receptor recycling |
GO_0035249 | Biological process | synaptic transmission, glutamatergic |
GO_0001726 | Cellular component | ruffle |
GO_0031982 | Cellular component | vesicle |
GO_0043197 | Cellular component | dendritic spine |
GO_0005769 | Cellular component | early endosome |
GO_0005813 | Cellular component | centrosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0030425 | Cellular component | dendrite |
GO_0005829 | Cellular component | cytosol |
GO_0014069 | Cellular component | postsynaptic density |
GO_0030426 | Cellular component | growth cone |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0030027 | Cellular component | lamellipodium |
GO_0005634 | Cellular component | nucleus |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0043539 | Molecular function | protein serine/threonine kinase activator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ALS2 |
Protein name | Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein) ALS2 Alsin Rho guanine nucleotide exchange factor ALS2 (Amyotrophic lateral sclerosis 2 isoform 2) Alsin Alsin Rho guanine nucleotide exchange factor ALS2 Alsin Rho guanine nucleotide exchange factor ALS2 (Amyotrophic lateral sclerosis 2 isoform 1) ALS2 protein |
Synonyms | ALS2CR6 KIAA1563 |
Description | FUNCTION: May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity). . |
Accessions | A0A7P0T8W6 ENST00000681768.1 A0A7P0Z4I4 ENST00000679516.1 [Q96Q42-1] ENST00000467448.5 [Q96Q42-2] A0A7P0T993 ENST00000680644.1 A0A7P0Z499 ENST00000681152.1 A0A7P0T958 A0A0S2Z5I4 J3KQ43 A0A7P0TBK0 A0A7P0T9V4 Q6IQ41 ENST00000679939.1 ENST00000681144.1 A0A0S2Z5Q7 ENST00000680726.1 J3KQ33 ENST00000679618.1 ENST00000679916.1 A0A7P0TAC4 A0A7P0T9R1 ENST00000680236.1 ENST00000679435.1 [Q96Q42-1] ENST00000679409.1 ENST00000264276.11 [Q96Q42-1] A0A7P0TAM1 H0Y696 A0A7P0TAH8 ENST00000680135.1 Q96Q42 A0A7P0T8T2 ENST00000680569.1 ENST00000410052.1 ENST00000680759.1 ENST00000680287.1 A0A7P0T9P3 A0A7P0T813 ENST00000681619.1 ENST00000439495.6 ENST00000679949.1 A0A7P0T8P3 ENST00000680814.1 A0A7P0T976 A0A7P0Z4F3 ENST00000681256.1 ENST00000681250.1 A0A7P0T951 A0A7P0T9K3 ENST00000680163.1 [Q96Q42-1] ENST00000680828.1 A0A7P0TBB0 ENST00000680861.1 [Q96Q42-1] A0A7P0Z4J9 ENST00000680927.1 ENST00000681808.1 ENST00000679503.1 [Q96Q42-2] ENST00000680188.1 [Q96Q42-2] ENST00000681558.1 ENST00000681716.1 A0A7P0Z4M6 ENST00000679728.1 ENST00000680149.1 A0A7P0T980 ENST00000680497.1 ENST00000681312.1 A0A7P0T8R1 A0A7P0T8F3 ENST00000681495.1 ENST00000409632 A0A7P0T9U5 ENST00000680000.1 A0A2X0SFA0 ENST00000679550.1 ENST00000409632.7 [Q96Q42-2] ENST00000681303.1 ENST00000680508.1 |