SNX4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000786Biological processpositive regulation of autophagosome assembly
GO_0032456Biological processendocytic recycling
GO_1903595Biological processpositive regulation of histamine secretion by mast cell
GO_0015031Biological processprotein transport
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005769Cellular componentearly endosome
GO_0031901Cellular componentearly endosome membrane
GO_0032991Cellular componentprotein-containing complex
GO_0005868Cellular componentcytoplasmic dynein complex
GO_0098830Cellular componentpresynaptic endosome
GO_0005737Cellular componentcytoplasm
GO_0031201Cellular componentSNARE complex
GO_0005158Molecular functioninsulin receptor binding
GO_1990459Molecular functiontransferrin receptor binding
GO_0005154Molecular functionepidermal growth factor receptor binding
GO_1990460Molecular functionleptin receptor binding
GO_0035091Molecular functionphosphatidylinositol binding
GO_0032266Molecular functionphosphatidylinositol-3-phosphate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSNX4
Protein nameSorting nexin-4
Sorting nexin 4
Synonyms
DescriptionFUNCTION: Involved in the regulation of endocytosis and in several stages of intracellular trafficking . Plays a role in recycling endocytosed transferrin receptor and prevent its degradation . Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A . .

AccessionsENST00000471751.5
F8WDD4
F8W9T3
ENST00000465505.2
O95219
ENST00000251775.9 [O95219-1]