VIPAS39 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0046907Biological processintracellular transport
GO_0006886Biological processintracellular protein transport
GO_0017185Biological processpeptidyl-lysine hydroxylation
GO_0043687Biological processpost-translational protein modification
GO_0090385Biological processphagosome-lysosome fusion
GO_0030154Biological processcell differentiation
GO_0008333Biological processendosome to lysosome transport
GO_0030199Biological processcollagen fibril organization
GO_0007034Biological processvacuolar transport
GO_0097352Biological processautophagosome maturation
GO_0032963Biological processcollagen metabolic process
GO_0030897Cellular componentHOPS complex
GO_0055037Cellular componentrecycling endosome
GO_0005769Cellular componentearly endosome
GO_0005794Cellular componentGolgi apparatus
GO_0099023Cellular componentvesicle tethering complex
GO_0005770Cellular componentlate endosome
GO_0005737Cellular componentcytoplasm
GO_0005768Cellular componentendosome
GO_0044877Molecular functionprotein-containing complex binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameVIPAS39
Protein nameSpermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction)
Spermatogenesis-defective protein 39 homolog (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction)
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
SynonymsVIPAR
SPE39
C14orf133
DescriptionFUNCTION: Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity . May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B . May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity). .

AccessionsENST00000556412.4
G3V549
ENST00000557658.6 [Q9H9C1-1]
G3V4K3
ENST00000557466.1
ENST00000327028.8 [Q9H9C1-2]
ENST00000448935.6 [Q9H9C1-2]
ENST00000343765.6 [Q9H9C1-1]
Q9H9C1
ENST00000553888.5 [Q9H9C1-1]