PTP4A3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1900746Biological processregulation of vascular endothelial growth factor signaling pathway
GO_1990830Biological processcellular response to leukemia inhibitory factor
GO_1901224Biological processpositive regulation of non-canonical NF-kappaB signal transduction
GO_0043117Biological processpositive regulation of vascular permeability
GO_1904951Biological processpositive regulation of establishment of protein localization
GO_0043542Biological processendothelial cell migration
GO_0007219Biological processNotch signaling pathway
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005769Cellular componentearly endosome
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004727Molecular functionprenylated protein tyrosine phosphatase activity
GO_0004725Molecular functionprotein tyrosine phosphatase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePTP4A3
Protein nameProtein tyrosine phosphatase 4A3 (Protein tyrosine phosphatase type IVA 3)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Protein tyrosine phosphatase 4A3
SynonymsPRL3
DescriptionFUNCTION: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. .

AccessionsENST00000524028.1
E5RFQ4
ENST00000523147.5
ENST00000707616.1 [O75365-1]
ENST00000520105.5 [O75365-2]
ENST00000349124.3 [O75365-1]
ENST00000707614.1 [O75365-2]
ENST00000521578.6 [O75365-1]
O75365
ENST00000622569.3 [O75365-1]
ENST00000633518.1 [O75365-1]
ENST00000680615.1 [O75365-1]
ENST00000707617.1 [O75365-1]
ENST00000329397.6 [O75365-1]
E5RGR3
ENST00000681443.1 [O75365-2]
ENST00000707619.1 [O75365-1]
ENST00000633621.1 [O75365-2]
ENST00000707620.1 [O75365-2]
ENST00000633262.1
ENST00000614325.2 [O75365-2]
ENST00000707618.1 [O75365-1]