MLC1 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	18 studies	38% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	7 studies	22% ± 7%	Explore
natural killer cell	5 studies	22% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	19% ± 4%	Explore
hematopoietic precursor cell	3 studies	21% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of MLC1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	19263.96	2632 / 2642	100%	534.43	704 / 705
prostate	19%	730.02	47 / 245	30%	1.22	153 / 502
lymph node	0%	0	0 / 0	38%	0.96	11 / 29
ovary	0%	0	0 / 180	36%	3.89	156 / 430
lung	1%	10.28	4 / 578	30%	1.32	347 / 1155
skin	0%	0	0 / 1809	28%	4.74	131 / 472
peripheral blood	24%	601.11	223 / 929	0%	0	0 / 0
uterus	2%	42.34	4 / 170	20%	0.84	93 / 459
kidney	0%	0	0 / 89	22%	0.38	198 / 901
eye	0%	0	0 / 0	20%	1.30	16 / 80
pancreas	0%	0	0 / 328	18%	1.12	32 / 178
breast	0%	0	0 / 459	18%	2.89	198 / 1118
esophagus	0%	0	0 / 1445	17%	0.60	32 / 183
thymus	0%	0	0 / 653	14%	0.58	86 / 605
tonsil	0%	0	0 / 0	13%	0.28	6 / 45
bladder	0%	0	0 / 21	10%	0.72	50 / 504
stomach	0%	0	0 / 359	8%	0.31	24 / 286
intestine	0%	1.48	1 / 966	7%	0.16	38 / 527
liver	0%	0	0 / 226	2%	0.05	10 / 406
adrenal gland	0%	6.23	1 / 258	1%	0.03	3 / 230
spleen	2%	38.65	4 / 241	0%	0	0 / 0
heart	0%	1.52	1 / 861	0%	0	0 / 0
blood vessel	0%	1.48	1 / 1335	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0072584	Biological process	caveolin-mediated endocytosis
GO_0047484	Biological process	regulation of response to osmotic stress
GO_0016192	Biological process	vesicle-mediated transport
GO_0071397	Biological process	cellular response to cholesterol
GO_0015031	Biological process	protein transport
GO_0032388	Biological process	positive regulation of intracellular transport
GO_0005886	Cellular component	plasma membrane
GO_0045121	Cellular component	membrane raft
GO_0031410	Cellular component	cytoplasmic vesicle
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0016020	Cellular component	membrane
GO_0055037	Cellular component	recycling endosome
GO_0005769	Cellular component	early endosome
GO_0005764	Cellular component	lysosome
GO_0030136	Cellular component	clathrin-coated vesicle
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005768	Cellular component	endosome
GO_0005901	Cellular component	caveola
GO_0016323	Cellular component	basolateral plasma membrane
GO_0044877	Molecular function	protein-containing complex binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

Gene name	MLC1
Protein name	Megalencephalic leukoencephalopathy with subcortical cysts 1 Modulator of VRAC current 1 Membrane protein MLC1
Synonyms	WKL1 KIAA0027
Description	FUNCTION: Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. .
Accessions	Q6NSL6 Q15049 ENST00000311597.10 [Q15049-1] A6PVC3 ENST00000395876.6 [Q15049-1] ENST00000442311.1

MLC1 report