ENTR1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ENTR1 at tissue level.

III. Associated gene sets

GO_0015031Biological processprotein transport
GO_0051301Biological processcell division
GO_0045724Biological processpositive regulation of cilium assembly
GO_1903566Biological processpositive regulation of protein localization to cilium
GO_0030030Biological processcell projection organization
GO_0032456Biological processendocytic recycling
GO_0032465Biological processregulation of cytokinesis
GO_0005813Cellular componentcentrosome
GO_0030904Cellular componentretromer complex
GO_0036064Cellular componentciliary basal body
GO_0005768Cellular componentendosome
GO_0030496Cellular componentmidbody
GO_0055037Cellular componentrecycling endosome
GO_0005769Cellular componentearly endosome
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameENTR1
Protein nameEndosome-associated-trafficking regulator 1 (Antigen NY-CO-3) (Serologically defined colon cancer antigen 3)
Endosome-associated-trafficking regulator 1
Endosome associated trafficking regulator 1
SynonymsSDCCAG3
DescriptionFUNCTION: Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis . Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 . Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 . Plays a role in the formation of cilia . Involved in cargo protein localization, such as PKD2, at primary cilia . Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis (By similarity). .

AccessionsB5MDD7
ENST00000371725.7 [Q96C92-4]
ENST00000357365.8 [Q96C92-1]
ENST00000446833.1
ENST00000371723.4
ENST00000417512.1
H7C331
A0A0A0MRP9
Q96C92
ENST00000298537.11 [Q96C92-2]