MVB12B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015031Biological processprotein transport
GO_0043162Biological processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0042058Biological processregulation of epidermal growth factor receptor signaling pathway
GO_0046755Biological processviral budding
GO_0019075Biological processvirus maturation
GO_0010008Cellular componentendosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0031902Cellular componentlate endosome membrane
GO_0005829Cellular componentcytosol
GO_0000813Cellular componentESCRT I complex
GO_0031982Cellular componentvesicle
GO_0005769Cellular componentearly endosome
GO_0005886Cellular componentplasma membrane
GO_0005770Cellular componentlate endosome
GO_0005634Cellular componentnucleus
GO_0043130Molecular functionubiquitin binding
GO_0005515Molecular functionprotein binding
GO_0008289Molecular functionlipid binding

IV. Literature review

[source]
Gene nameMVB12B
Protein nameMultivesicular body subunit 12B
Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B)
SynonymsFAM125B
C9orf28
DescriptionFUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.

AccessionsENST00000361171.8 [Q9H7P6-1]
Q9H7P6
ENST00000402437.2
ENST00000489637.3 [Q9H7P6-2]
F8W922