Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| mast cell | 8 studies | 23% ± 8% | |
| retinal cone cell | 6 studies | 23% ± 5% | |
| type I pneumocyte | 6 studies | 25% ± 7% | |
| glutamatergic neuron | 4 studies | 31% ± 10% | |
| GABAergic neuron | 3 studies | 22% ± 5% |
Insufficient scRNA-seq data for expression of AP1S3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 200.97 | 574 / 578 | 97% | 7.57 | 1117 / 1155 |
| prostate | 97% | 159.53 | 237 / 245 | 98% | 6.82 | 491 / 502 |
| thymus | 100% | 557.94 | 653 / 653 | 94% | 10.55 | 570 / 605 |
| kidney | 100% | 322.52 | 89 / 89 | 93% | 9.89 | 835 / 901 |
| pancreas | 96% | 98.35 | 314 / 328 | 94% | 13.09 | 168 / 178 |
| stomach | 87% | 152.62 | 311 / 359 | 94% | 6.16 | 268 / 286 |
| bladder | 81% | 216.05 | 17 / 21 | 91% | 6.61 | 457 / 504 |
| skin | 94% | 84.12 | 1695 / 1809 | 71% | 3.72 | 334 / 472 |
| breast | 80% | 59.07 | 368 / 459 | 84% | 3.86 | 934 / 1118 |
| intestine | 65% | 96.18 | 631 / 966 | 96% | 7.56 | 504 / 527 |
| esophagus | 62% | 125.55 | 894 / 1445 | 93% | 7.01 | 171 / 183 |
| uterus | 44% | 21.65 | 75 / 170 | 85% | 6.27 | 389 / 459 |
| adrenal gland | 90% | 57.18 | 231 / 258 | 36% | 1.33 | 82 / 230 |
| ovary | 48% | 28.42 | 87 / 180 | 61% | 2.23 | 261 / 430 |
| ureter | 0% | 0 | 0 / 0 | 100% | 21.17 | 1 / 1 |
| liver | 78% | 48.26 | 176 / 226 | 22% | 0.93 | 89 / 406 |
| spleen | 100% | 182.27 | 240 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 4.83 | 44 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 7.93 | 28 / 29 |
| brain | 89% | 104.89 | 2355 / 2642 | 4% | 0.10 | 25 / 705 |
| adipose | 83% | 70.94 | 1003 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 55% | 26.73 | 734 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 52% | 317.57 | 481 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 40% | 2.36 | 32 / 80 |
| heart | 24% | 12.67 | 204 / 861 | 0% | 0 | 0 / 0 |
| muscle | 5% | 1.88 | 41 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1903232 | Biological process | melanosome assembly |
| GO_0016192 | Biological process | vesicle-mediated transport |
| GO_0006886 | Biological process | intracellular protein transport |
| GO_0060155 | Biological process | platelet dense granule organization |
| GO_0006605 | Biological process | protein targeting |
| GO_0032588 | Cellular component | trans-Golgi network membrane |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005905 | Cellular component | clathrin-coated pit |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0030121 | Cellular component | AP-1 adaptor complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0005769 | Cellular component | early endosome |
| GO_0005515 | Molecular function | protein binding |
| GO_0035615 | Molecular function | clathrin adaptor activity |
| Gene name | AP1S3 |
| Protein name | Uncharacterized protein AP1S3 Adaptor related protein complex 1 subunit sigma 3 AP complex subunit sigma AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit of AP-1 clathrin) (Sigma-adaptin 1C) (Sigma1C-adaptin) Adaptor related protein complex 1 subunit sigma 3 (Adaptor-related protein complex 1, sigma 3 subunit, isoform CRA_b) |
| Synonyms | hCG_21436 |
| Description | FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking . . |
| Accessions | ENST00000415298.5 [Q96PC3-3] B8ZZZ1 A0A8V8TN74 G5E966 ENST00000699387.1 A0A8V8TPK7 Q53T10 ENST00000396654.7 [Q96PC3-4] ENST00000699392.1 ENST00000334271.7 ENST00000699385.1 A0A8V8TNP8 F8W8K9 ENST00000444408.1 ENST00000699390.1 ENST00000699389.1 Q53R44 A0A8V8TPZ3 ENST00000443700.5 [Q96PC3-2] ENST00000396653.2 ENST00000446015.6 [Q96PC3-1] ENST00000409375.1 C9JZK4 ENST00000699386.1 ENST00000699391.1 Q96PC3 A0A8V8TN69 |
