Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 18 studies | 52% ± 18% | |
basal cell | 15 studies | 34% ± 19% | |
epithelial cell | 10 studies | 35% ± 22% | |
secretory cell | 9 studies | 36% ± 17% | |
oligodendrocyte | 8 studies | 27% ± 10% | |
club cell | 7 studies | 39% ± 10% | |
respiratory goblet cell | 6 studies | 39% ± 24% | |
retinal rod cell | 6 studies | 22% ± 7% | |
brush cell | 5 studies | 36% ± 15% | |
duct epithelial cell | 4 studies | 50% ± 8% | |
ionocyte | 4 studies | 30% ± 8% | |
mucus secreting cell | 4 studies | 28% ± 8% | |
serous secreting cell | 3 studies | 40% ± 5% | |
intestinal crypt stem cell | 3 studies | 22% ± 6% | |
abnormal cell | 3 studies | 26% ± 7% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 24% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 1262.98 | 328 / 328 | 94% | 48.31 | 168 / 178 |
breast | 89% | 1584.68 | 408 / 459 | 96% | 46.62 | 1078 / 1118 |
stomach | 82% | 1391.82 | 295 / 359 | 95% | 53.04 | 272 / 286 |
prostate | 95% | 1991.71 | 232 / 245 | 79% | 24.56 | 399 / 502 |
uterus | 86% | 820.99 | 147 / 170 | 86% | 46.43 | 393 / 459 |
bladder | 67% | 1200.19 | 14 / 21 | 94% | 51.88 | 472 / 504 |
lung | 63% | 476.71 | 366 / 578 | 95% | 39.10 | 1098 / 1155 |
intestine | 57% | 1388.22 | 553 / 966 | 98% | 62.14 | 515 / 527 |
esophagus | 50% | 570.43 | 716 / 1445 | 96% | 35.18 | 176 / 183 |
thymus | 53% | 296.38 | 348 / 653 | 60% | 13.07 | 366 / 605 |
skin | 77% | 2031.30 | 1389 / 1809 | 31% | 6.90 | 144 / 472 |
brain | 80% | 963.38 | 2118 / 2642 | 20% | 3.24 | 144 / 705 |
tonsil | 0% | 0 | 0 / 0 | 100% | 38.19 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 49.15 | 1 / 1 |
kidney | 72% | 600.69 | 64 / 89 | 27% | 6.33 | 246 / 901 |
ovary | 22% | 78.26 | 39 / 180 | 66% | 15.13 | 282 / 430 |
eye | 0% | 0 | 0 / 0 | 86% | 20.75 | 69 / 80 |
adrenal gland | 63% | 713.89 | 163 / 258 | 18% | 6.45 | 42 / 230 |
spleen | 45% | 205.54 | 109 / 241 | 0% | 0 | 0 / 0 |
liver | 8% | 37.03 | 17 / 226 | 37% | 18.10 | 152 / 406 |
adipose | 40% | 166.56 | 477 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.49 | 1 / 29 |
blood vessel | 3% | 12.09 | 45 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 5.25 | 6 / 929 | 0% | 0 | 0 / 0 |
muscle | 0% | 1.11 | 2 / 803 | 0% | 0 | 0 / 0 |
heart | 0% | 1.89 | 2 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0006644 | Biological process | phospholipid metabolic process |
GO_0006672 | Biological process | ceramide metabolic process |
GO_0006670 | Biological process | sphingosine metabolic process |
GO_0030149 | Biological process | sphingolipid catabolic process |
GO_0046839 | Biological process | phospholipid dephosphorylation |
GO_0031901 | Cellular component | early endosome membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005886 | Cellular component | plasma membrane |
GO_0005901 | Cellular component | caveola |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005769 | Cellular component | early endosome |
GO_0008195 | Molecular function | phosphatidate phosphatase activity |
GO_0042392 | Molecular function | sphingosine-1-phosphate phosphatase activity |
GO_0106235 | Molecular function | ceramide-1-phosphate phosphatase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PLPP2 |
Protein name | Phospholipid phosphatase 2 Phospholipid phosphatase 2 (EC 3.1.3.-) (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 2) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c) |
Synonyms | LPP2 PPAP2C |
Description | FUNCTION: Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P . Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly . Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound . Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may regulate signal transduction in different cellular processes (Probable). Indirectly regulates, for instance, cell cycle G1/S phase transition through its phospholipid phosphatase activity (By similarity). . |
Accessions | A0A0J9YXA3 ENST00000327790.7 [O43688-2] K7EMK9 ENST00000633125.1 ENST00000591572.2 ENST00000434325.7 [O43688-1] ENST00000269812.7 [O43688-3] ENST00000586998.3 K7ENH4 O43688 |