Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 10 studies | 27% ± 10% | |
| glutamatergic neuron | 9 studies | 33% ± 22% | |
| retinal cone cell | 5 studies | 38% ± 22% | |
| GABAergic neuron | 5 studies | 41% ± 17% | |
| neuron | 4 studies | 26% ± 10% | |
| interneuron | 4 studies | 38% ± 19% | |
| endothelial cell | 3 studies | 24% ± 5% | |
| retinal bipolar neuron | 3 studies | 21% ± 3% | |
| retinal ganglion cell | 3 studies | 44% ± 17% | |
| astrocyte | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 39% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 5186.32 | 2628 / 2642 | 99% | 22.09 | 698 / 705 |
| thymus | 89% | 865.53 | 579 / 653 | 96% | 10.42 | 579 / 605 |
| lung | 58% | 517.10 | 337 / 578 | 69% | 4.34 | 798 / 1155 |
| adrenal gland | 24% | 161.06 | 62 / 258 | 96% | 14.68 | 220 / 230 |
| kidney | 24% | 166.97 | 21 / 89 | 95% | 9.05 | 859 / 901 |
| liver | 19% | 120.34 | 42 / 226 | 83% | 4.30 | 338 / 406 |
| muscle | 100% | 8540.00 | 803 / 803 | 0% | 0 | 0 / 0 |
| pancreas | 1% | 6.78 | 2 / 328 | 88% | 5.69 | 156 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 9.56 | 25 / 29 |
| heart | 85% | 1625.60 | 731 / 861 | 0% | 0 | 0 / 0 |
| stomach | 3% | 17.89 | 11 / 359 | 76% | 5.84 | 216 / 286 |
| ovary | 3% | 18.39 | 5 / 180 | 73% | 3.76 | 312 / 430 |
| intestine | 1% | 6.17 | 10 / 966 | 72% | 4.83 | 381 / 527 |
| prostate | 5% | 34.02 | 12 / 245 | 64% | 2.43 | 323 / 502 |
| breast | 25% | 169.33 | 113 / 459 | 41% | 2.48 | 453 / 1118 |
| skin | 12% | 95.73 | 222 / 1809 | 49% | 3.97 | 231 / 472 |
| esophagus | 2% | 16.53 | 29 / 1445 | 56% | 5.31 | 103 / 183 |
| uterus | 1% | 7.00 | 2 / 170 | 52% | 4.23 | 237 / 459 |
| bladder | 0% | 0 | 0 / 21 | 46% | 2.39 | 233 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 1.59 | 14 / 45 |
| blood vessel | 22% | 155.27 | 292 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 18% | 1.08 | 14 / 80 |
| adipose | 16% | 108.62 | 198 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 15% | 99.08 | 36 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 3% | 24.57 | 30 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1905515 | Biological process | non-motile cilium assembly |
| GO_0006821 | Biological process | chloride transport |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0031902 | Cellular component | late endosome membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0055037 | Cellular component | recycling endosome |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005769 | Cellular component | early endosome |
| GO_0031901 | Cellular component | early endosome membrane |
| GO_0055038 | Cellular component | recycling endosome membrane |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0008021 | Cellular component | synaptic vesicle |
| GO_0097546 | Cellular component | ciliary base |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0010008 | Cellular component | endosome membrane |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0015297 | Molecular function | antiporter activity |
| GO_0005247 | Molecular function | voltage-gated chloride channel activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005254 | Molecular function | chloride channel activity |
| Gene name | CLCN4 |
| Protein name | Chloride voltage-gated channel 4 Chloride channel protein Chloride Channel protein 4 H(+)/Cl(-) exchange transporter 4 (Chloride channel protein 4) (ClC-4) (Chloride transporter ClC-4) |
| Synonyms | hCG_401215 |
| Description | FUNCTION: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons . The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons . The presence of conserved gating glutamate residues is typical for family members that function as antiporters . . |
| Accessions | A0A6Q8PG54 ENST00000380829.5 ENST00000421085.7 P51793 ENST00000380833.9 [P51793-1] E9PFB5 ENST00000675769.1 ENST00000674669.1 [P51793-2] A0A7I2Y1J6 G3XAG5 A0A6Q8PF24 Q75N13 Q4G0X3 ENST00000454850.1 ENST00000675144.1 |
