RAB22A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006886Biological processintracellular protein transport
GO_0006897Biological processendocytosis
GO_0007032Biological processendosome organization
GO_0097494Biological processregulation of vesicle size
GO_0001726Cellular componentruffle
GO_0010008Cellular componentendosome membrane
GO_0015629Cellular componentactin cytoskeleton
GO_0070062Cellular componentextracellular exosome
GO_0045335Cellular componentphagocytic vesicle
GO_0005770Cellular componentlate endosome
GO_0005886Cellular componentplasma membrane
GO_0030670Cellular componentphagocytic vesicle membrane
GO_0012505Cellular componentendomembrane system
GO_0005769Cellular componentearly endosome
GO_0019003Molecular functionGDP binding
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAB22A
Protein nameRas-related protein Rab-22A (Rab-22)
SynonymsRAB22
DescriptionFUNCTION: Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes . Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth . Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form . .

AccessionsENST00000244040.4
Q9UL26