Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| conventional dendritic cell | 14 studies | 24% ± 10% | |
| dendritic cell | 5 studies | 24% ± 4% |
Insufficient scRNA-seq data for expression of CD1E at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 68% | 36.61 | 166 / 245 | 64% | 1.96 | 319 / 502 |
| lung | 69% | 55.16 | 400 / 578 | 62% | 3.84 | 713 / 1155 |
| thymus | 36% | 20.42 | 238 / 653 | 69% | 156.07 | 420 / 605 |
| breast | 41% | 15.62 | 189 / 459 | 63% | 3.70 | 707 / 1118 |
| skin | 69% | 100.86 | 1256 / 1809 | 35% | 1.26 | 163 / 472 |
| intestine | 63% | 25.98 | 604 / 966 | 33% | 0.87 | 172 / 527 |
| pancreas | 19% | 5.40 | 63 / 328 | 72% | 3.82 | 128 / 178 |
| bladder | 52% | 37.05 | 11 / 21 | 37% | 1.27 | 186 / 504 |
| stomach | 45% | 13.79 | 163 / 359 | 42% | 1.17 | 120 / 286 |
| uterus | 41% | 14.88 | 69 / 170 | 46% | 2.35 | 211 / 459 |
| esophagus | 51% | 40.70 | 741 / 1445 | 32% | 1.01 | 58 / 183 |
| kidney | 30% | 29.90 | 27 / 89 | 48% | 1.66 | 435 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 4.36 | 34 / 45 |
| spleen | 75% | 46.70 | 181 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 1.90 | 16 / 29 |
| adipose | 44% | 15.95 | 531 / 1204 | 0% | 0 | 0 / 0 |
| liver | 16% | 4.33 | 36 / 226 | 28% | 0.94 | 113 / 406 |
| blood vessel | 42% | 15.24 | 558 / 1335 | 0% | 0 | 0 / 0 |
| ovary | 7% | 1.78 | 12 / 180 | 29% | 1.32 | 123 / 430 |
| peripheral blood | 34% | 46.31 | 312 / 929 | 0% | 0 | 0 / 0 |
| adrenal gland | 11% | 1.87 | 29 / 258 | 8% | 0.16 | 18 / 230 |
| heart | 14% | 3.17 | 123 / 861 | 0% | 0 | 0 / 0 |
| brain | 1% | 0.16 | 18 / 2642 | 4% | 0.12 | 31 / 705 |
| muscle | 2% | 0.33 | 13 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0002250 | Biological process | adaptive immune response |
| GO_0048006 | Biological process | antigen processing and presentation, endogenous lipid antigen via MHC class Ib |
| GO_0001916 | Biological process | positive regulation of T cell mediated cytotoxicity |
| GO_0048007 | Biological process | antigen processing and presentation, exogenous lipid antigen via MHC class Ib |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005615 | Cellular component | extracellular space |
| GO_0043202 | Cellular component | lysosomal lumen |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005770 | Cellular component | late endosome |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005769 | Cellular component | early endosome |
| GO_0030883 | Molecular function | endogenous lipid antigen binding |
| GO_0030884 | Molecular function | exogenous lipid antigen binding |
| GO_0071723 | Molecular function | lipopeptide binding |
| Gene name | CD1E |
| Protein name | CD1e molecule CD1E protein T-cell surface glycoprotein CD1e, membrane-associated (hCD1e) (R2G1) (CD antigen CD1e) [Cleaved into: T-cell surface glycoprotein CD1e, soluble (sCD1e)] |
| Synonyms | |
| Description | FUNCTION: T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane-associated form is not active. . |
| Accessions | ENST00000368154.5 [P15812-11] ENST00000368157.5 [P15812-12] ENST00000368156.5 [P15812-6] ENST00000368162.2 ENST00000368160.7 [P15812-2] ENST00000368167.8 [P15812-1] A2RRL5 ENST00000368164.7 [P15812-10] ENST00000368165.7 [P15812-5] ENST00000368161.7 [P15812-3] ENST00000368166.7 [P15812-9] ENST00000444681.6 [P15812-13] H0Y345 ENST00000452291.6 [P15812-8] ENST00000368163.7 [P15812-4] ENST00000368155.7 [P15812-7] P15812 |