PTP4A2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	38 studies	35% ± 16%	Explore
CD8-positive, alpha-beta T cell	37 studies	32% ± 14%	Explore
B cell	33 studies	31% ± 14%	Explore
T cell	31 studies	32% ± 11%	Explore
macrophage	31 studies	31% ± 11%	Explore
fibroblast	30 studies	32% ± 15%	Explore
conventional dendritic cell	28 studies	44% ± 20%	Explore
classical monocyte	27 studies	49% ± 21%	Explore
endothelial cell	26 studies	28% ± 13%	Explore
CD4-positive, alpha-beta T cell	25 studies	31% ± 16%	Explore
non-classical monocyte	24 studies	62% ± 21%	Explore
dendritic cell	23 studies	44% ± 22%	Explore
regulatory T cell	23 studies	29% ± 11%	Explore
monocyte	21 studies	44% ± 15%	Explore
epithelial cell	19 studies	45% ± 25%	Explore
mast cell	18 studies	31% ± 15%	Explore
pericyte	18 studies	24% ± 8%	Explore
memory B cell	18 studies	31% ± 13%	Explore
gamma-delta T cell	18 studies	37% ± 16%	Explore
smooth muscle cell	16 studies	27% ± 7%	Explore
mature NK T cell	16 studies	34% ± 13%	Explore
plasmacytoid dendritic cell	16 studies	33% ± 12%	Explore
basal cell	16 studies	39% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	14 studies	40% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	13 studies	39% ± 17%	Explore
naive B cell	13 studies	28% ± 10%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	34% ± 17%	Explore
CD16-negative, CD56-bright natural killer cell, human	13 studies	31% ± 15%	Explore
mucosal invariant T cell	13 studies	28% ± 9%	Explore
myeloid cell	13 studies	41% ± 21%	Explore
endothelial cell of lymphatic vessel	12 studies	29% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	32% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	12 studies	38% ± 18%	Explore
ciliated cell	11 studies	38% ± 18%	Explore
oligodendrocyte	11 studies	36% ± 13%	Explore
plasma cell	10 studies	32% ± 14%	Explore
secretory cell	10 studies	49% ± 24%	Explore
effector memory CD8-positive, alpha-beta T cell	10 studies	49% ± 23%	Explore
endothelial cell of vascular tree	10 studies	30% ± 12%	Explore
type I pneumocyte	9 studies	31% ± 16%	Explore
club cell	9 studies	37% ± 20%	Explore
platelet	9 studies	42% ± 17%	Explore
goblet cell	9 studies	31% ± 10%	Explore
connective tissue cell	9 studies	33% ± 6%	Explore
plasmablast	8 studies	49% ± 22%	Explore
neutrophil	8 studies	28% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	8 studies	35% ± 10%	Explore
leukocyte	8 studies	46% ± 13%	Explore
endothelial cell of artery	8 studies	27% ± 7%	Explore
mesothelial cell	8 studies	34% ± 19%	Explore
vein endothelial cell	8 studies	25% ± 7%	Explore
T follicular helper cell	8 studies	35% ± 13%	Explore
microglial cell	8 studies	26% ± 9%	Explore
alveolar macrophage	7 studies	28% ± 9%	Explore
precursor B cell	7 studies	40% ± 18%	Explore
innate lymphoid cell	7 studies	32% ± 6%	Explore
type II pneumocyte	6 studies	42% ± 17%	Explore
hematopoietic precursor cell	6 studies	50% ± 27%	Explore
ionocyte	6 studies	29% ± 9%	Explore
respiratory goblet cell	6 studies	38% ± 15%	Explore
mononuclear phagocyte	6 studies	47% ± 18%	Explore
abnormal cell	6 studies	29% ± 11%	Explore
myofibroblast cell	6 studies	30% ± 14%	Explore
progenitor cell	6 studies	35% ± 16%	Explore
lymphocyte	6 studies	33% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	28% ± 9%	Explore
exhausted T cell	5 studies	41% ± 23%	Explore
transit amplifying cell	5 studies	24% ± 8%	Explore
pro-B cell	5 studies	39% ± 20%	Explore
brush cell	5 studies	30% ± 13%	Explore
immature B cell	5 studies	37% ± 19%	Explore
astrocyte	5 studies	25% ± 7%	Explore
adipocyte	5 studies	19% ± 3%	Explore
capillary endothelial cell	5 studies	25% ± 10%	Explore
CD4-positive helper T cell	5 studies	33% ± 15%	Explore
intermediate monocyte	5 studies	50% ± 26%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	46% ± 18%	Explore
erythrocyte	5 studies	45% ± 18%	Explore
deuterosomal cell	4 studies	24% ± 7%	Explore
pancreatic A cell	4 studies	51% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	27% ± 12%	Explore
retinal pigment epithelial cell	4 studies	44% ± 20%	Explore
Mueller cell	4 studies	27% ± 5%	Explore
acinar cell	4 studies	46% ± 29%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	66% ± 14%	Explore
neuron	4 studies	39% ± 15%	Explore
granulocyte	4 studies	33% ± 20%	Explore
GABAergic neuron	4 studies	35% ± 13%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	40% ± 24%	Explore
double negative thymocyte	4 studies	51% ± 26%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	25% ± 5%	Explore
duct epithelial cell	3 studies	28% ± 6%	Explore
squamous epithelial cell	3 studies	40% ± 26%	Explore
pancreatic D cell	3 studies	50% ± 26%	Explore
type B pancreatic cell	3 studies	55% ± 18%	Explore
monocyte-derived dendritic cell	3 studies	49% ± 23%	Explore
intestinal crypt stem cell	3 studies	27% ± 8%	Explore
neural crest cell	3 studies	22% ± 2%	Explore
IgG plasma cell	3 studies	20% ± 3%	Explore
thymocyte	3 studies	39% ± 21%	Explore
megakaryocyte	3 studies	54% ± 7%	Explore
retina horizontal cell	3 studies	36% ± 15%	Explore
adventitial cell	3 studies	23% ± 4%	Explore
mucus secreting cell	3 studies	29% ± 1%	Explore
serous secreting cell	3 studies	24% ± 6%	Explore
tissue-resident macrophage	3 studies	34% ± 18%	Explore
melanocyte	3 studies	25% ± 7%	Explore
germinal center B cell	3 studies	39% ± 3%	Explore
inflammatory macrophage	3 studies	28% ± 4%	Explore
luminal cell of prostate epithelium	3 studies	60% ± 11%	Explore
glutamatergic neuron	3 studies	55% ± 10%	Explore
pancreatic ductal cell	3 studies	79% ± 14%	Explore
hematopoietic stem cell	3 studies	47% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	70% ± 13%	Explore
enterocyte	3 studies	24% ± 6%	Explore
enteroendocrine cell	3 studies	33% ± 9%	Explore
group 3 innate lymphoid cell	3 studies	38% ± 14%	Explore
T-helper 17 cell	3 studies	35% ± 3%	Explore
T-helper 1 cell	3 studies	46% ± 4%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	31% ± 11%	Explore
hepatocyte	3 studies	44% ± 17%	Explore
oligodendrocyte precursor cell	3 studies	21% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	18 studies	42% ± 19%	Explore
lung	17 studies	34% ± 15%	Explore
intestine	11 studies	28% ± 11%	Explore
brain	10 studies	32% ± 13%	Explore
bone marrow	6 studies	35% ± 19%	Explore
eye	5 studies	29% ± 8%	Explore
liver	5 studies	36% ± 18%	Explore
pancreas	4 studies	53% ± 18%	Explore
kidney	4 studies	22% ± 5%	Explore
lymph node	4 studies	26% ± 3%	Explore
uterus	4 studies	37% ± 19%	Explore
breast	4 studies	36% ± 12%	Explore
skin	3 studies	26% ± 8%	Explore
thymus	3 studies	51% ± 25%	Explore
prostate	3 studies	55% ± 16%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	13458.73	459 / 459	100%	201.91	1118 / 1118
lung	100%	11080.07	578 / 578	100%	97.99	1155 / 1155
ovary	100%	9122.39	180 / 180	100%	99.66	430 / 430
stomach	100%	8768.25	359 / 359	100%	102.22	286 / 286
uterus	100%	8609.53	170 / 170	100%	104.91	459 / 459
brain	100%	16022.49	2641 / 2642	100%	112.86	705 / 705
thymus	100%	10593.38	653 / 653	100%	165.48	604 / 605
intestine	100%	10250.25	966 / 966	100%	99.76	526 / 527
bladder	100%	13704.95	21 / 21	100%	111.22	503 / 504
prostate	100%	9390.64	245 / 245	100%	77.55	501 / 502
esophagus	100%	8088.77	1442 / 1445	100%	89.71	183 / 183
pancreas	99%	4741.41	326 / 328	100%	99.02	178 / 178
kidney	100%	7521.66	89 / 89	98%	71.45	887 / 901
skin	100%	8468.95	1801 / 1809	98%	98.59	464 / 472
liver	97%	4503.86	219 / 226	99%	50.23	400 / 406
adrenal gland	100%	7575.52	258 / 258	93%	45.60	214 / 230
adipose	100%	14970.53	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	110.11	29 / 29
muscle	100%	20283.23	803 / 803	0%	0	0 / 0
spleen	100%	10022.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	77.83	45 / 45
ureter	0%	0	0 / 0	100%	74.52	1 / 1
blood vessel	100%	9811.83	1334 / 1335	0%	0	0 / 0
peripheral blood	99%	10151.23	920 / 929	0%	0	0 / 0
heart	95%	10114.10	820 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	90%	44.89	72 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

IV. Literature review

[source]

Gene name	PTP4A2
Protein name	Protein tyrosine phosphatase 4A2 Protein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2)
Synonyms	PTPCAAX2 BM-008 PRL2
Description	FUNCTION: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. .
Accessions	Q12974 ENST00000457805.6 [Q12974-3] E9PJC0 ENST00000528253.3 ENST00000468531.1 E9PML8 ENST00000470404.5 ENST00000602683.5 [Q12974-4] ENST00000649841.1 [Q12974-1] ENST00000647444.2 [Q12974-1] E9PL34 E9PMY3 ENST00000602725.5 [Q12974-1] E9PRR9 ENST00000534796.5 ENST00000532001.6

GO_0005829	Cellular component	cytosol
GO_0005769	Cellular component	early endosome
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0004727	Molecular function	prenylated protein tyrosine phosphatase activity
GO_0004725	Molecular function	protein tyrosine phosphatase activity
GO_0005515	Molecular function	protein binding

PTP4A2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review