ASTN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048105Biological processestablishment of body hair planar orientation
GO_0015031Biological processprotein transport
GO_0001764Biological processneuron migration
GO_0007158Biological processneuron cell-cell adhesion
GO_0034394Biological processprotein localization to cell surface
GO_2000009Biological processnegative regulation of protein localization to cell surface
GO_0043204Cellular componentperikaryon
GO_0005768Cellular componentendosome
GO_0005938Cellular componentcell cortex
GO_0005770Cellular componentlate endosome
GO_0030136Cellular componentclathrin-coated vesicle
GO_0060187Cellular componentcell pole
GO_0016020Cellular componentmembrane
GO_0005769Cellular componentearly endosome
GO_0043533Molecular functioninositol 1,3,4,5 tetrakisphosphate binding
GO_0005509Molecular functioncalcium ion binding

IV. Literature review

[source]
Gene nameASTN2
Protein nameAstrotactin-2
Astrotactin 2
ASTN2 protein
SynonymsKIAA0634
hCG_2036769
DescriptionFUNCTION: Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6). .

AccessionsENST00000288520.9 [O75129-4]
B7ZKP5
ENST00000361209.6 [O75129-2]
O75129
H7C3I6
ENST00000361477.8
ENST00000373986.7
A0A0A0MRH9
ENST00000313400.9 [O75129-1]
B7ZKP3
B2RCB6
B7ZKP4
H0Y3A8
X6R5P2
ENST00000358637.4
ENST00000341734.8 [O75129-6]
ENST00000417725.1