ANKRD13B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ANKRD13B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ANKRD13B at tissue level.

III. Associated gene sets

GO_0002091Biological processnegative regulation of receptor internalization
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005886Cellular componentplasma membrane
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005770Cellular componentlate endosome
GO_0005737Cellular componentcytoplasm
GO_0005769Cellular componentearly endosome
GO_0140036Molecular functionubiquitin-modified protein reader activity

IV. Literature review

[source]
Gene nameANKRD13B
Protein nameAnkyrin repeat domain 13B
Ankyrin repeat domain-containing protein 13B
ANKRD13B protein
Synonyms
DescriptionFUNCTION: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. .

FUNCTION: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. .

AccessionsENST00000614878.4 [Q86YJ7-1]
Q86YJ7
Q6P5X6
K7EKP0
K7ENT0
ENST00000488766.5 [Q86YJ7-1]
ENST00000394859.8 [Q86YJ7-1]
ENST00000579719.1
ENST00000583728.5