Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 12 studies | 29% ± 12% | |
microglial cell | 11 studies | 34% ± 11% | |
endothelial cell | 10 studies | 27% ± 11% | |
glutamatergic neuron | 10 studies | 36% ± 25% | |
macrophage | 8 studies | 38% ± 18% | |
oligodendrocyte precursor cell | 8 studies | 30% ± 11% | |
astrocyte | 8 studies | 39% ± 17% | |
epithelial cell | 5 studies | 26% ± 10% | |
adipocyte | 5 studies | 22% ± 3% | |
GABAergic neuron | 5 studies | 51% ± 19% | |
smooth muscle cell | 4 studies | 19% ± 2% | |
dendritic cell | 4 studies | 26% ± 5% | |
pericyte | 4 studies | 23% ± 7% | |
retina horizontal cell | 4 studies | 38% ± 20% | |
myeloid cell | 4 studies | 29% ± 7% | |
goblet cell | 4 studies | 35% ± 27% | |
endothelial cell of lymphatic vessel | 4 studies | 21% ± 5% | |
fibroblast | 4 studies | 25% ± 5% | |
interneuron | 4 studies | 53% ± 20% | |
GABAergic interneuron | 3 studies | 20% ± 3% | |
alveolar macrophage | 3 studies | 39% ± 8% | |
type I pneumocyte | 3 studies | 19% ± 2% | |
type II pneumocyte | 3 studies | 24% ± 3% | |
basal cell | 3 studies | 29% ± 11% | |
neuron | 3 studies | 47% ± 22% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 12 studies | 35% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1337.67 | 1445 / 1445 | 99% | 19.93 | 182 / 183 |
stomach | 100% | 1027.65 | 359 / 359 | 99% | 18.32 | 284 / 286 |
lung | 100% | 1265.76 | 576 / 578 | 99% | 14.91 | 1148 / 1155 |
intestine | 100% | 2213.66 | 966 / 966 | 99% | 19.34 | 521 / 527 |
breast | 100% | 1864.15 | 459 / 459 | 98% | 33.63 | 1101 / 1118 |
pancreas | 99% | 667.49 | 324 / 328 | 98% | 11.20 | 174 / 178 |
kidney | 100% | 1462.65 | 89 / 89 | 96% | 12.39 | 869 / 901 |
prostate | 100% | 1166.10 | 245 / 245 | 96% | 13.43 | 481 / 502 |
bladder | 100% | 1391.24 | 21 / 21 | 96% | 13.06 | 482 / 504 |
thymus | 100% | 1623.19 | 653 / 653 | 95% | 10.09 | 572 / 605 |
skin | 100% | 1801.89 | 1809 / 1809 | 94% | 14.53 | 445 / 472 |
uterus | 100% | 1156.14 | 170 / 170 | 93% | 11.35 | 429 / 459 |
adrenal gland | 100% | 3910.17 | 258 / 258 | 93% | 12.09 | 214 / 230 |
liver | 100% | 854.11 | 226 / 226 | 83% | 6.12 | 339 / 406 |
ovary | 100% | 1978.78 | 180 / 180 | 81% | 4.79 | 347 / 430 |
brain | 99% | 824.40 | 2624 / 2642 | 77% | 4.84 | 543 / 705 |
adipose | 100% | 1415.92 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1441.20 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 1588.87 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1040.84 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 95% | 899.66 | 814 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 11.17 | 42 / 45 |
eye | 0% | 0 | 0 / 0 | 69% | 5.39 | 55 / 80 |
lymph node | 0% | 0 | 0 / 0 | 52% | 4.08 | 15 / 29 |
peripheral blood | 35% | 209.01 | 326 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001919 | Biological process | regulation of receptor recycling |
GO_0001704 | Biological process | formation of primary germ layer |
GO_0007492 | Biological process | endoderm development |
GO_0007018 | Biological process | microtubule-based movement |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0032801 | Biological process | receptor catabolic process |
GO_0045022 | Biological process | early endosome to late endosome transport |
GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
GO_0006895 | Biological process | Golgi to endosome transport |
GO_0005874 | Cellular component | microtubule |
GO_0005769 | Cellular component | early endosome |
GO_0031901 | Cellular component | early endosome membrane |
GO_0005871 | Cellular component | kinesin complex |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005768 | Cellular component | endosome |
GO_0005819 | Cellular component | spindle |
GO_0005547 | Molecular function | phosphatidylinositol-3,4,5-trisphosphate binding |
GO_0008574 | Molecular function | plus-end-directed microtubule motor activity |
GO_0043325 | Molecular function | phosphatidylinositol-3,4-bisphosphate binding |
GO_0032266 | Molecular function | phosphatidylinositol-3-phosphate binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005524 | Molecular function | ATP binding |
GO_0080025 | Molecular function | phosphatidylinositol-3,5-bisphosphate binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | KIF16B |
Protein name | Kinesin-like protein KIF16B (Sorting nexin-23) Kinesin family member 16B |
Synonyms | C20orf23 KIAA1590 SNX23 |
Description | FUNCTION: Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. . |
Accessions | H0Y534 ENST00000354981.7 [Q96L93-1] ENST00000408042.5 [Q96L93-2] Q96L93 A0A1B0GVS8 ENST00000450176.1 ENST00000636835.1 A0A1B0GTU3 ENST00000635823.2 |