Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 30 studies | 39% ± 21% | |
naive B cell | 20 studies | 64% ± 19% | |
plasmacytoid dendritic cell | 17 studies | 34% ± 11% | |
precursor B cell | 7 studies | 66% ± 21% | |
immature B cell | 6 studies | 83% ± 11% | |
memory B cell | 4 studies | 26% ± 8% | |
germinal center B cell | 4 studies | 70% ± 11% | |
pro-B cell | 3 studies | 21% ± 2% |
Insufficient scRNA-seq data for expression of TCL1A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
spleen | 99% | 2251.53 | 239 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 93% | 420.84 | 27 / 29 |
peripheral blood | 91% | 2968.36 | 850 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 51% | 7.65 | 23 / 45 |
lung | 5% | 6.25 | 31 / 578 | 41% | 2.33 | 474 / 1155 |
intestine | 20% | 187.12 | 197 / 966 | 20% | 3.42 | 108 / 527 |
skin | 0% | 0.04 | 1 / 1809 | 38% | 7.05 | 178 / 472 |
pancreas | 0% | 0 | 0 / 328 | 34% | 11.22 | 60 / 178 |
thymus | 6% | 60.46 | 39 / 653 | 22% | 4.66 | 132 / 605 |
breast | 0% | 0 | 0 / 459 | 28% | 2.43 | 309 / 1118 |
stomach | 2% | 2.23 | 6 / 359 | 24% | 3.24 | 69 / 286 |
bladder | 0% | 0 | 0 / 21 | 19% | 2.11 | 98 / 504 |
esophagus | 2% | 3.16 | 25 / 1445 | 16% | 1.34 | 29 / 183 |
uterus | 0% | 0 | 0 / 170 | 16% | 0.79 | 72 / 459 |
kidney | 6% | 14.75 | 5 / 89 | 7% | 0.40 | 63 / 901 |
prostate | 2% | 12.66 | 4 / 245 | 10% | 0.50 | 51 / 502 |
ovary | 2% | 1.74 | 4 / 180 | 10% | 0.36 | 41 / 430 |
liver | 1% | 1.23 | 3 / 226 | 8% | 0.92 | 31 / 406 |
adrenal gland | 0% | 0 | 0 / 258 | 3% | 0.07 | 7 / 230 |
adipose | 2% | 5.19 | 21 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.06 | 1 / 80 |
blood vessel | 1% | 5.61 | 12 / 1335 | 0% | 0 | 0 / 0 |
brain | 0% | 0.02 | 1 / 2642 | 1% | 1.16 | 5 / 705 |
heart | 0% | 0.54 | 2 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0043539 | Molecular function | protein serine/threonine kinase activator activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TCL1A |
Protein name | T-cell leukemia/lymphoma protein 1A (Oncogene TCL-1) (Oncogene TCL1) (Protein p14 TCL1) TCL1 family AKT coactivator A |
Synonyms | TCL1 |
Description | FUNCTION: Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. . |
Accessions | ENST00000554119.5 H0YJR9 ENST00000555202.1 ENST00000402399.6 G3V4T4 ENST00000554012.5 ENST00000557043.4 ENST00000555886.5 ENST00000556450.5 ENST00000556156.1 P56279 |