FCER2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of FCER2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	76%	58.21	437 / 578	31%	1.65	354 / 1155
spleen	100%	3392.66	241 / 241	0%	0	0 / 0
peripheral blood	99%	6378.47	919 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	182.84	28 / 29
adipose	91%	192.52	1093 / 1204	0%	0	0 / 0
breast	71%	90.28	325 / 459	19%	1.48	216 / 1118
intestine	71%	274.51	685 / 966	17%	1.50	89 / 527
bladder	71%	76.67	15 / 21	16%	2.62	79 / 504
stomach	36%	20.21	129 / 359	24%	1.37	68 / 286
esophagus	44%	30.13	635 / 1445	15%	0.94	28 / 183
skin	29%	18.92	520 / 1809	30%	6.76	141 / 472
liver	43%	19.89	98 / 226	8%	1.01	31 / 406
thymus	28%	76.15	182 / 653	17%	1.77	104 / 605
tonsil	0%	0	0 / 0	42%	5.46	19 / 45
pancreas	3%	1.01	9 / 328	29%	6.85	51 / 178
kidney	24%	25.79	21 / 89	6%	0.35	55 / 901
prostate	17%	11.37	42 / 245	10%	0.37	49 / 502
uterus	20%	8.21	34 / 170	6%	0.37	28 / 459
heart	25%	12.85	212 / 861	0%	0	0 / 0
blood vessel	21%	25.63	280 / 1335	0%	0	0 / 0
adrenal gland	16%	6.31	40 / 258	5%	0.20	12 / 230
brain	5%	2.82	132 / 2642	15%	0.75	105 / 705
muscle	14%	5.77	112 / 803	0%	0	0 / 0
ovary	11%	6.76	20 / 180	3%	0.09	11 / 430
eye	0%	0	0 / 0	4%	0.06	3 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051712	Biological process	positive regulation of killing of cells of another organism
GO_0042116	Biological process	macrophage activation
GO_0051770	Biological process	positive regulation of nitric-oxide synthase biosynthetic process
GO_0044419	Biological process	biological process involved in interspecies interaction between organisms
GO_0002925	Biological process	positive regulation of humoral immune response mediated by circulating immunoglobulin
GO_0038095	Biological process	Fc-epsilon receptor signaling pathway
GO_0006955	Biological process	immune response
GO_0160006	Biological process	Fc receptor-mediated immune complex endocytosis
GO_0051000	Biological process	positive regulation of nitric-oxide synthase activity
GO_0002450	Biological process	B cell antigen processing and presentation
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0070062	Cellular component	extracellular exosome
GO_0019863	Molecular function	IgE binding
GO_0030246	Molecular function	carbohydrate binding
GO_0005178	Molecular function	integrin binding
GO_0002020	Molecular function	protease binding
GO_0019769	Molecular function	low-affinity IgE receptor activity
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

Gene name	FCER2
Protein name	FCER2 protein CD23 antigen Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form] Fc epsilon receptor II
Synonyms	CLEC4J IGEBF CD23A FCE2
Description	FUNCTION: Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells . On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway . .
Accessions	K3W4U1 ENST00000593418.1 P06734 Q30219 Q30218 ENST00000360067.8 M0R1R5 ENST00000597921.6 ENST00000346664.9

FCER2 report