Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 34 studies | 39% ± 20% | |
memory B cell | 17 studies | 45% ± 16% | |
naive B cell | 17 studies | 43% ± 13% | |
immature B cell | 4 studies | 28% ± 2% | |
germinal center B cell | 3 studies | 39% ± 16% |
Insufficient scRNA-seq data for expression of TNFRSF13C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 87% | 182.86 | 502 / 578 | 86% | 5.51 | 989 / 1155 |
brain | 74% | 122.63 | 1951 / 2642 | 89% | 4.30 | 627 / 705 |
skin | 83% | 300.49 | 1499 / 1809 | 77% | 5.73 | 365 / 472 |
stomach | 59% | 120.77 | 213 / 359 | 59% | 3.92 | 170 / 286 |
esophagus | 38% | 95.70 | 542 / 1445 | 76% | 3.63 | 139 / 183 |
intestine | 52% | 1445.81 | 505 / 966 | 55% | 3.48 | 288 / 527 |
adrenal gland | 91% | 147.61 | 234 / 258 | 14% | 0.37 | 32 / 230 |
breast | 47% | 86.58 | 218 / 459 | 54% | 2.50 | 599 / 1118 |
lymph node | 0% | 0 | 0 / 0 | 100% | 110.35 | 29 / 29 |
spleen | 100% | 10331.28 | 241 / 241 | 0% | 0 | 0 / 0 |
uterus | 20% | 17.52 | 34 / 170 | 80% | 3.40 | 365 / 459 |
peripheral blood | 99% | 3743.11 | 917 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 8.61 | 40 / 45 |
bladder | 24% | 73.10 | 5 / 21 | 59% | 3.60 | 298 / 504 |
prostate | 48% | 91.46 | 118 / 245 | 26% | 0.78 | 131 / 502 |
ovary | 8% | 6.87 | 15 / 180 | 65% | 2.05 | 279 / 430 |
kidney | 49% | 147.90 | 44 / 89 | 20% | 0.54 | 176 / 901 |
pancreas | 2% | 1.49 | 6 / 328 | 67% | 6.21 | 119 / 178 |
thymus | 19% | 208.00 | 124 / 653 | 39% | 2.48 | 234 / 605 |
heart | 39% | 42.46 | 334 / 861 | 0% | 0 | 0 / 0 |
adipose | 34% | 71.54 | 405 / 1204 | 0% | 0 | 0 / 0 |
liver | 16% | 14.53 | 37 / 226 | 13% | 1.26 | 52 / 406 |
eye | 0% | 0 | 0 / 0 | 23% | 0.42 | 18 / 80 |
muscle | 14% | 14.72 | 113 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 8% | 37.88 | 108 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0031295 | Biological process | T cell costimulation |
GO_0002250 | Biological process | adaptive immune response |
GO_0042102 | Biological process | positive regulation of T cell proliferation |
GO_0031296 | Biological process | B cell costimulation |
GO_0030890 | Biological process | positive regulation of B cell proliferation |
GO_0033209 | Biological process | tumor necrosis factor-mediated signaling pathway |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0038023 | Molecular function | signaling receptor activity |
Gene name | TNFRSF13C |
Protein name | Tumor necrosis factor receptor superfamily member 13C (B-cell-activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD antigen CD268) Tumor necrosis factor receptor superfamily, member 13C BAFF receptor BAFF receptor (BAFF-R) (Tumor necrosis factor receptor superfamily, member 13C) |
Synonyms | BR3 BAFFR BAFF-R hCG_41562 |
Description | FUNCTION: B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. . |
Accessions | S6FW99 C8ZLJ6 Q5H8V1 Q96RJ3 ENST00000291232.5 [Q96RJ3-1] |