CTPS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006139Biological processnucleobase-containing compound metabolic process
GO_0042100Biological processB cell proliferation
GO_0006541Biological processglutamine metabolic process
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0019856Biological processpyrimidine nucleobase biosynthetic process
GO_0042098Biological processT cell proliferation
GO_0006241Biological processCTP biosynthetic process
GO_0044210Biological process'de novo' CTP biosynthetic process
GO_0097268Cellular componentcytoophidium
GO_0005829Cellular componentcytosol
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0003883Molecular functionCTP synthase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameCTPS1
Protein nameCTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)
CTP synthase 1
CTP synthase (EC 6.3.4.2) (UTP--ammonia ligase)
SynonymsCTPS
DescriptionFUNCTION: This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity. .

FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. .

FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. .

FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. .

FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. .

FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. .

FUNCTION: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. .

AccessionsENST00000649864.1
ENST00000372616.1 [P17812-1]
ENST00000696070.1 [P17812-2]
ENST00000648914.1
B4E1E0
ENST00000696111.1
ENST00000463423.6
A0A8Q3WL12
A0A8Q3WL00
A0A3B3ITB8
A0A3B3ISY3
P17812
A0A8Q3WKZ7
ENST00000470271.6 [P17812-1]
A0A3B3ITF6
ENST00000649124.2 [P17812-1]
ENST00000650070.2 [P17812-1]
ENST00000648020.2
ENST00000470271.5
A0A3B3ITH9
ENST00000475060.1
ENST00000696110.1
A0A8Q3WL40
A0A3B3IRQ8
ENST00000649215.1
ENST00000696107.1
ENST00000696108.1
A0A3B3IRI2
ENST00000463285.7