Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| erythrocyte | 12 studies | 50% ± 19% | |
| erythroblast | 6 studies | 45% ± 22% | |
| oligodendrocyte | 6 studies | 21% ± 6% | |
| kidney loop of Henle epithelial cell | 4 studies | 20% ± 2% | |
| GABAergic neuron | 3 studies | 30% ± 7% | |
| glutamatergic neuron | 3 studies | 41% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1577.44 | 245 / 245 | 100% | 25.61 | 502 / 502 |
| brain | 100% | 1257.23 | 2640 / 2642 | 100% | 13.00 | 704 / 705 |
| breast | 100% | 1397.54 | 459 / 459 | 100% | 15.66 | 1114 / 1118 |
| thymus | 100% | 1656.24 | 653 / 653 | 99% | 11.38 | 600 / 605 |
| kidney | 100% | 2390.51 | 89 / 89 | 98% | 12.69 | 886 / 901 |
| uterus | 100% | 1414.69 | 170 / 170 | 97% | 10.20 | 447 / 459 |
| lung | 99% | 1068.03 | 571 / 578 | 98% | 13.15 | 1135 / 1155 |
| skin | 100% | 1426.38 | 1808 / 1809 | 97% | 12.35 | 458 / 472 |
| liver | 100% | 1743.63 | 226 / 226 | 96% | 9.73 | 389 / 406 |
| ovary | 100% | 1296.64 | 180 / 180 | 95% | 8.08 | 409 / 430 |
| adrenal gland | 100% | 2265.06 | 258 / 258 | 94% | 10.62 | 216 / 230 |
| bladder | 100% | 1521.62 | 21 / 21 | 93% | 8.72 | 470 / 504 |
| pancreas | 100% | 823.38 | 327 / 328 | 93% | 6.39 | 165 / 178 |
| esophagus | 100% | 1478.15 | 1445 / 1445 | 91% | 9.15 | 167 / 183 |
| stomach | 100% | 1051.99 | 359 / 359 | 87% | 5.88 | 249 / 286 |
| intestine | 100% | 1411.98 | 966 / 966 | 84% | 5.63 | 445 / 527 |
| adipose | 100% | 1350.41 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2549.61 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1447.72 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 10.15 | 45 / 45 |
| blood vessel | 100% | 1270.37 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 1380.37 | 846 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 2023.23 | 912 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 10.16 | 28 / 29 |
| eye | 0% | 0 | 0 / 0 | 91% | 7.87 | 73 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0009589 | Biological process | detection of UV |
| GO_0006091 | Biological process | generation of precursor metabolites and energy |
| GO_0071549 | Biological process | cellular response to dexamethasone stimulus |
| GO_0008203 | Biological process | cholesterol metabolic process |
| GO_0010288 | Biological process | response to lead ion |
| GO_0034379 | Biological process | very-low-density lipoprotein particle assembly |
| GO_0060586 | Biological process | multicellular organismal-level iron ion homeostasis |
| GO_0006783 | Biological process | heme biosynthetic process |
| GO_0006784 | Biological process | heme A biosynthetic process |
| GO_0046685 | Biological process | response to arsenic-containing substance |
| GO_0045471 | Biological process | response to ethanol |
| GO_0006785 | Biological process | heme B biosynthetic process |
| GO_0070541 | Biological process | response to platinum ion |
| GO_0030218 | Biological process | erythrocyte differentiation |
| GO_0046501 | Biological process | protoporphyrinogen IX metabolic process |
| GO_0009416 | Biological process | response to light stimulus |
| GO_0046984 | Biological process | regulation of hemoglobin biosynthetic process |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0051597 | Biological process | response to methylmercury |
| GO_0017085 | Biological process | response to insecticide |
| GO_0048034 | Biological process | heme O biosynthetic process |
| GO_0010999 | Biological process | regulation of eIF2 alpha phosphorylation by heme |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0008198 | Molecular function | ferrous iron binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0020037 | Molecular function | heme binding |
| GO_0030350 | Molecular function | iron-responsive element binding |
| GO_0051537 | Molecular function | 2 iron, 2 sulfur cluster binding |
| GO_0004325 | Molecular function | ferrochelatase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | FECH |
| Protein name | Ferrochelatase (EC 4.98.1.1) Ferrochelatase Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the ferrous insertion into protoporphyrin IX. . FUNCTION: Catalyzes the ferrous insertion into protoporphyrin IX. . FUNCTION: Catalyzes the ferrous insertion into protoporphyrin IX. . |
| Accessions | K7EJX5 ENST00000652755.1 [P22830-2] K7EJM8 ENST00000591977.5 Q8TD50 ENST00000382873.8 K7ELX4 P22830 ENST00000585494.5 ENST00000262093.11 [P22830-1] A0A499FJN5 ENST00000592699.6 |
