GIP report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GIP at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GIP at tissue level.

III. Associated gene sets

GO_0019233Biological processsensory perception of pain
GO_0070328Biological processtriglyceride homeostasis
GO_0050796Biological processregulation of insulin secretion
GO_0035640Biological processexploration behavior
GO_0043200Biological processresponse to amino acid
GO_0010828Biological processpositive regulation of glucose transmembrane transport
GO_0043434Biological processresponse to peptide hormone
GO_0009749Biological processresponse to glucose
GO_0007165Biological processsignal transduction
GO_0008344Biological processadult locomotory behavior
GO_0048678Biological processresponse to axon injury
GO_0014070Biological processresponse to organic cyclic compound
GO_0060291Biological processlong-term synaptic potentiation
GO_0007565Biological processfemale pregnancy
GO_0042304Biological processregulation of fatty acid biosynthetic process
GO_0032024Biological processpositive regulation of insulin secretion
GO_0010447Biological processresponse to acidic pH
GO_0042594Biological processresponse to starvation
GO_0055123Biological processdigestive system development
GO_0033993Biological processresponse to lipid
GO_0043950Biological processpositive regulation of cAMP-mediated signaling
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007613Biological processmemory
GO_0031018Biological processendocrine pancreas development
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0010269Biological processresponse to selenium ion
GO_0038192Biological processgastric inhibitory peptide signaling pathway
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0043025Cellular componentneuronal cell body
GO_0034774Cellular componentsecretory granule lumen
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005179Molecular functionhormone activity
GO_0031769Molecular functionglucagon receptor binding
GO_0031767Molecular functiongastric inhibitory polypeptide receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGIP
Protein nameGastric inhibitory polypeptide (GIP) (Glucose-dependent insulinotropic polypeptide) (Incretin hormone)
Synonyms
DescriptionFUNCTION: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.

AccessionsP09681
ENST00000357424.2