Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 8 studies | 27% ± 11% | |
| secretory cell | 7 studies | 45% ± 15% | |
| epithelial cell | 5 studies | 41% ± 19% | |
| duct epithelial cell | 4 studies | 44% ± 18% | |
| kidney loop of Henle epithelial cell | 3 studies | 34% ± 11% | |
| pancreatic ductal cell | 3 studies | 70% ± 5% |
Insufficient scRNA-seq data for expression of MMP7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 2658.46 | 328 / 328 | 88% | 1047.74 | 157 / 178 |
| kidney | 100% | 6593.64 | 89 / 89 | 59% | 329.80 | 531 / 901 |
| prostate | 73% | 1991.65 | 180 / 245 | 64% | 141.96 | 322 / 502 |
| breast | 64% | 2683.81 | 292 / 459 | 41% | 137.90 | 453 / 1118 |
| lung | 52% | 265.46 | 298 / 578 | 50% | 128.28 | 575 / 1155 |
| uterus | 68% | 872.39 | 115 / 170 | 34% | 170.06 | 154 / 459 |
| bladder | 43% | 315.81 | 9 / 21 | 35% | 96.90 | 177 / 504 |
| skin | 70% | 1061.77 | 1274 / 1809 | 1% | 1.65 | 6 / 472 |
| ovary | 3% | 26.76 | 5 / 180 | 69% | 261.61 | 295 / 430 |
| stomach | 10% | 25.31 | 36 / 359 | 41% | 99.51 | 118 / 286 |
| esophagus | 13% | 158.48 | 190 / 1445 | 35% | 118.69 | 64 / 183 |
| intestine | 1% | 3.07 | 13 / 966 | 46% | 142.63 | 240 / 527 |
| liver | 9% | 37.89 | 21 / 226 | 16% | 60.70 | 63 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 20% | 26.20 | 9 / 45 |
| adipose | 17% | 106.72 | 203 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 4% | 10.52 | 25 / 653 | 12% | 20.03 | 75 / 605 |
| peripheral blood | 14% | 377.01 | 133 / 929 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.99 | 9 / 2642 | 3% | 3.36 | 23 / 705 |
| blood vessel | 4% | 14.68 | 47 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 17.34 | 1 / 29 |
| muscle | 0% | 3.02 | 4 / 803 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 1.47 | 1 / 258 | 0% | 0 | 0 / 230 |
| heart | 0% | 1.73 | 1 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0031293 | Biological process | membrane protein intracellular domain proteolysis |
| GO_0002780 | Biological process | antibacterial peptide biosynthetic process |
| GO_0050829 | Biological process | defense response to Gram-negative bacterium |
| GO_0030198 | Biological process | extracellular matrix organization |
| GO_0022617 | Biological process | extracellular matrix disassembly |
| GO_0030574 | Biological process | collagen catabolic process |
| GO_0050830 | Biological process | defense response to Gram-positive bacterium |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0006508 | Biological process | proteolysis |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0002779 | Biological process | antibacterial peptide secretion |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_0006509 | Biological process | membrane protein ectodomain proteolysis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0004175 | Molecular function | endopeptidase activity |
| GO_0008237 | Molecular function | metallopeptidase activity |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0004222 | Molecular function | metalloendopeptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| Gene name | MMP7 |
| Protein name | Matrix metalloproteinase 7 Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase) |
| Synonyms | MPSL1 PUMP1 |
| Description | FUNCTION: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. . |
| Accessions | A5GZ72 ENST00000260227.5 P09237 |