GO_0031293 | membrane protein intracellular domain proteolysis | OmnibusX

membrane protein intracellular domain proteolysis

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	TGFB1 SPPL2B HM13	neuron hematopoietic stem cell	6 studies
Group 2	PSENEN MBTPS1 SPPL2A ADAM9 NCSTN APH1A	epithelial cell	6 studies
Group 3	APH1B MBTPS2 RHBDD1	dopaminergic neuron GABAergic neuron glutamatergic neuron	6 studies
Group 4	MMP7	secretory cell basal cell duct epithelial cell epithelial cell pancreatic ductal cell	23 studies

II. Literature review

Name	membrane protein intracellular domain proteolysis
ID	GO_0031293
collection_id	Biological process
Related synonym	membrane protein solubilization
Description	The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.
External URL
Genes	PSENEN ADAM9 TGFB1 SPPL2B NCSTN HM13 MBTPS2 SPPL2C gamma-secretase_alpha1a-psen2_human-1 gamma-secretase_alpha1a-psen1_human gamma-secretase_alpha1b-psen2_human-1 MMP7 gamma-secretase_alpha1b-psen1_human MBTPS1 RHBDD1 APH1B SPPL2A APH1A