Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 28% ± 10% | |
B cell | 14 studies | 22% ± 7% | |
microglial cell | 10 studies | 29% ± 11% | |
oligodendrocyte precursor cell | 10 studies | 28% ± 13% | |
macrophage | 9 studies | 35% ± 11% | |
fibroblast | 9 studies | 20% ± 3% | |
astrocyte | 9 studies | 30% ± 11% | |
oligodendrocyte | 9 studies | 27% ± 9% | |
glutamatergic neuron | 8 studies | 39% ± 23% | |
pericyte | 8 studies | 21% ± 5% | |
interneuron | 7 studies | 32% ± 17% | |
epithelial cell | 7 studies | 32% ± 12% | |
naive B cell | 7 studies | 19% ± 4% | |
myeloid cell | 6 studies | 28% ± 6% | |
adipocyte | 6 studies | 23% ± 5% | |
dendritic cell | 6 studies | 24% ± 8% | |
GABAergic neuron | 6 studies | 41% ± 15% | |
neuron | 5 studies | 40% ± 12% | |
smooth muscle cell | 5 studies | 20% ± 2% | |
mast cell | 5 studies | 24% ± 7% | |
memory B cell | 5 studies | 16% ± 1% | |
endothelial cell of lymphatic vessel | 5 studies | 25% ± 3% | |
non-classical monocyte | 4 studies | 20% ± 5% | |
retinal cone cell | 4 studies | 20% ± 3% | |
cardiac muscle cell | 4 studies | 26% ± 4% | |
lymphocyte | 4 studies | 27% ± 6% | |
monocyte | 4 studies | 34% ± 6% | |
T cell | 4 studies | 24% ± 3% | |
goblet cell | 4 studies | 28% ± 15% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 16% ± 1% | |
CD4-positive, alpha-beta T cell | 3 studies | 19% ± 3% | |
classical monocyte | 3 studies | 22% ± 5% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
precursor B cell | 3 studies | 25% ± 3% | |
immature B cell | 3 studies | 23% ± 6% | |
retina horizontal cell | 3 studies | 23% ± 5% | |
retinal bipolar neuron | 3 studies | 18% ± 3% | |
ciliated cell | 3 studies | 24% ± 1% | |
glycinergic amacrine cell | 3 studies | 20% ± 4% | |
retinal rod cell | 3 studies | 25% ± 4% | |
regulatory T cell | 3 studies | 19% ± 4% | |
neural progenitor cell | 3 studies | 28% ± 3% | |
leukocyte | 3 studies | 26% ± 6% | |
myofibroblast cell | 3 studies | 21% ± 5% | |
alveolar macrophage | 3 studies | 31% ± 12% | |
club cell | 3 studies | 22% ± 9% | |
natural killer cell | 3 studies | 21% ± 2% | |
type I pneumocyte | 3 studies | 23% ± 6% | |
basal cell | 3 studies | 33% ± 14% | |
transit amplifying cell | 3 studies | 31% ± 20% | |
plasmacytoid dendritic cell | 3 studies | 19% ± 4% | |
abnormal cell | 3 studies | 26% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2220.49 | 1445 / 1445 | 100% | 16.49 | 183 / 183 |
lung | 100% | 2785.91 | 578 / 578 | 100% | 14.32 | 1155 / 1155 |
breast | 100% | 3017.81 | 459 / 459 | 100% | 18.40 | 1117 / 1118 |
brain | 100% | 1645.36 | 2636 / 2642 | 100% | 14.98 | 705 / 705 |
prostate | 100% | 2360.48 | 245 / 245 | 99% | 14.03 | 499 / 502 |
ovary | 100% | 2606.86 | 180 / 180 | 99% | 11.22 | 427 / 430 |
thymus | 100% | 2609.38 | 653 / 653 | 99% | 14.36 | 600 / 605 |
intestine | 100% | 2473.20 | 966 / 966 | 99% | 11.13 | 521 / 527 |
bladder | 100% | 2556.90 | 21 / 21 | 99% | 11.05 | 498 / 504 |
uterus | 100% | 2882.42 | 170 / 170 | 99% | 12.52 | 453 / 459 |
stomach | 100% | 1648.38 | 359 / 359 | 98% | 12.06 | 281 / 286 |
pancreas | 99% | 1203.07 | 326 / 328 | 98% | 12.03 | 175 / 178 |
kidney | 100% | 1551.61 | 89 / 89 | 95% | 12.14 | 853 / 901 |
skin | 100% | 2739.91 | 1809 / 1809 | 93% | 11.59 | 438 / 472 |
adrenal gland | 100% | 1570.61 | 257 / 258 | 91% | 7.33 | 209 / 230 |
liver | 100% | 882.05 | 226 / 226 | 70% | 4.40 | 286 / 406 |
adipose | 100% | 3082.28 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2877.28 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 14.44 | 29 / 29 |
spleen | 100% | 2970.05 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.01 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.44 | 1 / 1 |
heart | 99% | 1419.01 | 854 / 861 | 0% | 0 | 0 / 0 |
muscle | 99% | 972.30 | 792 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 2318.34 | 907 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 66% | 5.42 | 53 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071300 | Biological process | cellular response to retinoic acid |
GO_0033363 | Biological process | secretory granule organization |
GO_0055025 | Biological process | positive regulation of cardiac muscle tissue development |
GO_0030316 | Biological process | osteoclast differentiation |
GO_2000224 | Biological process | regulation of testosterone biosynthetic process |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0035729 | Biological process | cellular response to hepatocyte growth factor stimulus |
GO_0007165 | Biological process | signal transduction |
GO_0071294 | Biological process | cellular response to zinc ion |
GO_1990830 | Biological process | cellular response to leukemia inhibitory factor |
GO_0060430 | Biological process | lung saccule development |
GO_0019933 | Biological process | cAMP-mediated signaling |
GO_0014074 | Biological process | response to purine-containing compound |
GO_0033762 | Biological process | response to glucagon |
GO_0046889 | Biological process | positive regulation of lipid biosynthetic process |
GO_0010944 | Biological process | negative regulation of transcription by competitive promoter binding |
GO_0007623 | Biological process | circadian rhythm |
GO_0007409 | Biological process | axonogenesis |
GO_0045672 | Biological process | positive regulation of osteoclast differentiation |
GO_0060509 | Biological process | type I pneumocyte differentiation |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_1904322 | Biological process | cellular response to forskolin |
GO_0050821 | Biological process | protein stabilization |
GO_0046879 | Biological process | hormone secretion |
GO_0045600 | Biological process | positive regulation of fat cell differentiation |
GO_0042789 | Biological process | mRNA transcription by RNA polymerase II |
GO_0007613 | Biological process | memory |
GO_0008361 | Biological process | regulation of cell size |
GO_0007595 | Biological process | lactation |
GO_0021983 | Biological process | pituitary gland development |
GO_0006468 | Biological process | protein phosphorylation |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0046887 | Biological process | positive regulation of hormone secretion |
GO_0040018 | Biological process | positive regulation of multicellular organism growth |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_1990589 | Cellular component | ATF4-CREB1 transcription factor complex |
GO_0000791 | Cellular component | euchromatin |
GO_0005654 | Cellular component | nucleoplasm |
GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0019899 | Molecular function | enzyme binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0035497 | Molecular function | cAMP response element binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CREB1 |
Protein name | Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1) Uncharacterized protein CREB1 cAMP responsive element binding protein 1 (cDNA, FLJ93156, Homo sapiens cAMP responsive element binding protein 1 (CREB1),transcript variant B, mRNA) CREB1 protein (cAMP responsive element binding protein 1) (cDNA, FLJ96224, Homo sapiens cAMP responsive element binding protein 1 (CREB1),transcript variant A, mRNA) cAMP responsive element binding protein 1 |
Synonyms | hCG_15208 |
Description | FUNCTION: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters (By similarity). Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation . Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells (By similarity). Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling (By similarity). . |
Accessions | ENST00000445803.5 C9J276 Q53RU9 Q53X93 P16220 H7C1R5 ENST00000421139.5 H7C3I0 Q5U0J5 ENST00000418081.5 ENST00000455757.1 ENST00000448277.5 C9J896 ENST00000430624.5 [P16220-2] ENST00000457101.5 Q4ZG78 C9JBT4 ENST00000414681.1 C9J4L5 ENST00000353267.8 [P16220-2] ENST00000452474.5 ENST00000432329.6 [P16220-1] E7EWP8 C9JCI4 |