TXNRD2 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	22% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TXNRD2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	3322.19	226 / 226	100%	21.17	406 / 406
thymus	100%	2103.91	653 / 653	100%	10.62	604 / 605
skin	100%	1553.87	1808 / 1809	100%	14.22	471 / 472
prostate	100%	3522.36	245 / 245	100%	38.73	500 / 502
brain	99%	1732.66	2624 / 2642	100%	12.71	705 / 705
kidney	100%	2292.37	89 / 89	99%	10.64	892 / 901
adrenal gland	100%	4306.58	258 / 258	99%	14.19	227 / 230
lung	100%	1849.64	577 / 578	98%	11.03	1137 / 1155
breast	100%	1703.19	459 / 459	98%	10.96	1098 / 1118
ovary	100%	2217.91	180 / 180	98%	8.23	422 / 430
intestine	100%	1683.11	966 / 966	98%	9.70	517 / 527
pancreas	100%	1087.34	328 / 328	98%	9.56	174 / 178
stomach	100%	2292.01	359 / 359	97%	8.15	278 / 286
uterus	100%	1632.96	170 / 170	97%	11.29	446 / 459
esophagus	100%	1420.27	1445 / 1445	96%	6.30	175 / 183
bladder	100%	1544.38	21 / 21	92%	10.49	464 / 504
adipose	100%	1326.08	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	14.89	80 / 80
lymph node	0%	0	0 / 0	100%	13.71	29 / 29
spleen	100%	2229.95	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	8.95	45 / 45
ureter	0%	0	0 / 0	100%	20.55	1 / 1
blood vessel	100%	1485.60	1334 / 1335	0%	0	0 / 0
muscle	100%	1604.93	801 / 803	0%	0	0 / 0
heart	98%	1644.09	846 / 861	0%	0	0 / 0
peripheral blood	98%	1089.58	907 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0045454	Biological process	cell redox homeostasis
GO_0055093	Biological process	response to hyperoxia
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0010269	Biological process	response to selenium ion
GO_0098869	Biological process	cellular oxidant detoxification
GO_0000305	Biological process	response to oxygen radical
GO_0030424	Cellular component	axon
GO_0005829	Cellular component	cytosol
GO_0043025	Cellular component	neuronal cell body
GO_0005759	Cellular component	mitochondrial matrix
GO_0005737	Cellular component	cytoplasm
GO_0005739	Cellular component	mitochondrion
GO_0030425	Cellular component	dendrite
GO_0044877	Molecular function	protein-containing complex binding
GO_0042803	Molecular function	protein homodimerization activity
GO_0004791	Molecular function	thioredoxin-disulfide reductase (NADPH) activity
GO_0005515	Molecular function	protein binding
GO_0050660	Molecular function	flavin adenine dinucleotide binding

Gene name	TXNRD2
Protein name	Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Selenoprotein Z) (SelZ) (TR-beta) (Thioredoxin reductase TR3) Thioredoxin reductase 2 TXNRD2 protein thioredoxin-disulfide reductase (EC 1.8.1.9)
Synonyms	TRXR2 KIAA1652
Description	FUNCTION: Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis . Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. .
Accessions	ENST00000542719.6 [Q9NNW7-3] ENST00000400525.6 ENST00000400518.5 ENST00000400519.6 A0A096LP96 A0A096LPB7 ENST00000475995.3 A4FTY4 A0A096LPK7 Q9NNW7 A0A096LPD9 ENST00000400521.7 [Q9NNW7-1] ENST00000485358.5 A0A096LNY7 A0A0U1RQX0 E7EWK1 ENST00000474308.5 ENST00000462330.5 ENST00000491939.6 D3YTF8 A0A096LPH4 Q17RE6 A0A182DWF2 A0A182DWF3 ENST00000634537.1 ENST00000462843.2 ENST00000334363.14

TXNRD2 report