Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 38% ± 23% | |
| oligodendrocyte precursor cell | 5 studies | 35% ± 11% | |
| type B pancreatic cell | 4 studies | 65% ± 22% | |
| neuron | 4 studies | 17% ± 3% | |
| GABAergic neuron | 4 studies | 39% ± 15% | |
| astrocyte | 4 studies | 23% ± 7% | |
| pancreatic D cell | 3 studies | 44% ± 20% | |
| interneuron | 3 studies | 35% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 4655.81 | 2607 / 2642 | 87% | 10.50 | 612 / 705 |
| pancreas | 99% | 2986.15 | 325 / 328 | 71% | 26.04 | 127 / 178 |
| thymus | 85% | 1137.65 | 555 / 653 | 34% | 1.81 | 204 / 605 |
| prostate | 71% | 643.24 | 174 / 245 | 45% | 1.27 | 226 / 502 |
| breast | 46% | 546.03 | 211 / 459 | 58% | 3.67 | 646 / 1118 |
| stomach | 77% | 1111.43 | 276 / 359 | 2% | 0.18 | 6 / 286 |
| adrenal gland | 27% | 617.56 | 69 / 258 | 49% | 4.54 | 112 / 230 |
| lung | 69% | 1604.60 | 398 / 578 | 6% | 0.19 | 74 / 1155 |
| uterus | 45% | 516.61 | 77 / 170 | 5% | 0.11 | 25 / 459 |
| heart | 43% | 245.44 | 368 / 861 | 0% | 0 | 0 / 0 |
| muscle | 33% | 200.24 | 269 / 803 | 0% | 0 | 0 / 0 |
| intestine | 23% | 103.98 | 225 / 966 | 5% | 0.80 | 25 / 527 |
| bladder | 14% | 58.43 | 3 / 21 | 2% | 0.12 | 10 / 504 |
| kidney | 10% | 44.63 | 9 / 89 | 2% | 0.05 | 14 / 901 |
| ovary | 10% | 63.18 | 18 / 180 | 0% | 0.02 | 2 / 430 |
| esophagus | 2% | 8.89 | 29 / 1445 | 5% | 0.22 | 9 / 183 |
| adipose | 6% | 23.74 | 68 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 4% | 17.87 | 50 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 3% | 0.15 | 14 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
| skin | 0% | 2.45 | 8 / 1809 | 1% | 0.06 | 7 / 472 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.03 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006813 | Biological process | potassium ion transport |
| GO_0061535 | Biological process | glutamate secretion, neurotransmission |
| GO_0055085 | Biological process | transmembrane transport |
| GO_1905604 | Biological process | negative regulation of blood-brain barrier permeability |
| GO_0010989 | Biological process | negative regulation of low-density lipoprotein particle clearance |
| GO_0032868 | Biological process | response to insulin |
| GO_1900721 | Biological process | positive regulation of uterine smooth muscle relaxation |
| GO_0050905 | Biological process | neuromuscular process |
| GO_0009268 | Biological process | response to pH |
| GO_0098662 | Biological process | inorganic cation transmembrane transport |
| GO_0001678 | Biological process | intracellular glucose homeostasis |
| GO_0007565 | Biological process | female pregnancy |
| GO_0071805 | Biological process | potassium ion transmembrane transport |
| GO_0008542 | Biological process | visual learning |
| GO_0046676 | Biological process | negative regulation of insulin secretion |
| GO_0016525 | Biological process | negative regulation of angiogenesis |
| GO_0035774 | Biological process | positive regulation of insulin secretion involved in cellular response to glucose stimulus |
| GO_0060253 | Biological process | negative regulation of glial cell proliferation |
| GO_0010043 | Biological process | response to zinc ion |
| GO_0043268 | Biological process | positive regulation of potassium ion transport |
| GO_0007613 | Biological process | memory |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_1905075 | Biological process | positive regulation of tight junction disassembly |
| GO_0061855 | Biological process | negative regulation of neuroblast migration |
| GO_0032760 | Biological process | positive regulation of tumor necrosis factor production |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_1990573 | Biological process | potassium ion import across plasma membrane |
| GO_0031004 | Cellular component | potassium ion-transporting ATPase complex |
| GO_0008282 | Cellular component | inward rectifying potassium channel |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0030672 | Cellular component | synaptic vesicle membrane |
| GO_0042383 | Cellular component | sarcolemma |
| GO_0043531 | Molecular function | ADP binding |
| GO_0140359 | Molecular function | ABC-type transporter activity |
| GO_0019829 | Molecular function | ATPase-coupled monoatomic cation transmembrane transporter activity |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005267 | Molecular function | potassium channel activity |
| GO_0008281 | Molecular function | sulfonylurea receptor activity |
| GO_0042626 | Molecular function | ATPase-coupled transmembrane transporter activity |
| GO_0015272 | Molecular function | ATP-activated inward rectifier potassium channel activity |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| Gene name | ABCC8 |
| Protein name | ATP binding cassette subfamily C member 8 ATP-binding cassette subfamily C member 8 ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1) |
| Synonyms | SUR SUR1 HRINS |
| Description | FUNCTION: Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release. . |
| Accessions | ENST00000683725.1 A0A2R8Y475 ENST00000646003.1 A0A2R8Y781 ENST00000647086.1 A0A804HI74 ENST00000646993.1 A0A2R8Y6I7 ENST00000644649.1 ENST00000683562.1 A0A2R8YHG6 ENST00000643260.1 ENST00000684555.1 ENST00000647015.1 ENST00000682288.1 ENST00000645884.1 A0A220SZZ5 ENST00000645760.1 A0A2R8YDG6 ENST00000682965.1 A0A2R8Y775 ENST00000684711.1 ENST00000684571.1 ENST00000642271.1 H0YDH8 ENST00000527905.5 A0A804HL76 Q09428 ENST00000647013.1 ENST00000646276.1 ENST00000531891.1 A0A804HK92 A0A2R8Y605 ENST00000682140.1 E9PK50 A0A2R8YCG4 H0YE33 ENST00000389817.8 [Q09428-1] A0A2R8YGQ6 A0A2R8YDB5 ENST00000644675.1 ENST00000646207.1 A0A804HJG5 A0A804HLA1 ENST00000644757.1 ENST00000646902.1 A0A2R8YDG0 A0A2R8YDE9 ENST00000645744.1 ENST00000642579.1 ENST00000643925.1 A0A2R8Y4Z4 A0A2R8Y6Q0 A0A2R8YD94 ENST00000526168.5 A0A2R8Y5V4 ENST00000644484.1 A0A2R8Y4V0 ENST00000683456.1 A0A2R8YG67 A0A804HJH4 ENST00000684288.1 ENST00000682204.1 ENST00000528374.2 A0A804HK47 H0YF51 A0A2R8Y5X1 ENST00000642902.1 ENST00000644542.1 [Q09428-3] A0A2R8Y5I7 A0A2R8YFU3 A0A2R8Y698 H0YEA9 ENST00000644447.1 A0A804HJZ2 ENST00000684593.1 [Q09428-3] ENST00000683136.1 ENST00000646592.1 A0A2R8YEE5 A0A2R8Y7I1 ENST00000643562.1 ENST00000644472.1 ENST00000302539.9 [Q09428-2] ENST00000646737.1 A0A2R8YDX3 ENST00000645076.1 ENST00000645417.1 ENST00000644772.1 A0A2R8Y6B7 A0A2R8Y3M7 ENST00000647158.1 A0A2R8Y5D8 A0A2R8YFB3 ENST00000531642.5 ENST00000532728.6 |
