Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 11 studies | 29% ± 12% | |
| GABAergic neuron | 5 studies | 45% ± 20% | |
| GABAergic interneuron | 3 studies | 20% ± 1% | |
| glutamatergic neuron | 3 studies | 35% ± 20% | |
| interneuron | 3 studies | 52% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 26% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 10578.52 | 2630 / 2642 | 100% | 379.45 | 702 / 705 |
| adrenal gland | 16% | 430.85 | 41 / 258 | 68% | 32.08 | 156 / 230 |
| breast | 60% | 994.81 | 276 / 459 | 8% | 0.51 | 86 / 1118 |
| adipose | 61% | 1248.36 | 735 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 59% | 1251.10 | 571 / 966 | 1% | 0.18 | 6 / 527 |
| uterus | 50% | 922.86 | 85 / 170 | 10% | 1.18 | 46 / 459 |
| esophagus | 55% | 1227.31 | 797 / 1445 | 1% | 0.05 | 1 / 183 |
| ovary | 12% | 272.30 | 22 / 180 | 36% | 6.87 | 154 / 430 |
| thymus | 26% | 333.66 | 172 / 653 | 13% | 1.48 | 76 / 605 |
| stomach | 32% | 848.45 | 114 / 359 | 2% | 0.09 | 5 / 286 |
| prostate | 20% | 279.24 | 49 / 245 | 1% | 0.06 | 7 / 502 |
| heart | 15% | 182.54 | 129 / 861 | 0% | 0 | 0 / 0 |
| bladder | 14% | 195.43 | 3 / 21 | 1% | 0.02 | 3 / 504 |
| pancreas | 1% | 8.87 | 3 / 328 | 4% | 0.38 | 8 / 178 |
| lung | 3% | 38.23 | 20 / 578 | 2% | 0.15 | 21 / 1155 |
| skin | 2% | 21.07 | 34 / 1809 | 3% | 0.34 | 15 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.65 | 2 / 45 |
| blood vessel | 3% | 41.06 | 35 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.07 | 1 / 80 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.04 | 8 / 901 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.11 | 3 / 406 |
| muscle | 0% | 1.43 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032355 | Biological process | response to estradiol |
| GO_0007188 | Biological process | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
| GO_0007283 | Biological process | spermatogenesis |
| GO_1901032 | Biological process | negative regulation of response to reactive oxygen species |
| GO_0010524 | Biological process | positive regulation of calcium ion transport into cytosol |
| GO_0019933 | Biological process | cAMP-mediated signaling |
| GO_0060732 | Biological process | positive regulation of inositol phosphate biosynthetic process |
| GO_0045471 | Biological process | response to ethanol |
| GO_0033555 | Biological process | multicellular organismal response to stress |
| GO_0030154 | Biological process | cell differentiation |
| GO_0043950 | Biological process | positive regulation of cAMP-mediated signaling |
| GO_0051057 | Biological process | positive regulation of small GTPase mediated signal transduction |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0046545 | Biological process | development of primary female sexual characteristics |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0043235 | Cellular component | receptor complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0009986 | Cellular component | cell surface |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005768 | Cellular component | endosome |
| GO_0005901 | Cellular component | caveola |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0017046 | Molecular function | peptide hormone binding |
| GO_0031267 | Molecular function | small GTPase binding |
| GO_0008528 | Molecular function | G protein-coupled peptide receptor activity |
| GO_0042923 | Molecular function | neuropeptide binding |
| GO_0004999 | Molecular function | vasoactive intestinal polypeptide receptor activity |
| GO_0008179 | Molecular function | adenylate cyclase binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ADCYAP1R1 |
| Protein name | Adenylate cyclase activating polypeptide 1 (Pituitary) receptor type I Pituitary adenylate cyclase activating polypeptide 1 receptor type I HopII variant ADCYAP receptor type I Pituitary adenylate cyclase-activating polypeptide type I receptor (PACAP type I receptor) (PACAP-R-1) (PACAP-R1) Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop splice variant Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hip variant Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hop splice variant |
| Synonyms | tcag7.689 |
| Description | FUNCTION: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. |
| Accessions | ENST00000436116.1 ENST00000431811.5 H0Y813 Q6S992 ENST00000409363.5 [P41586-3] P41586 A0A090N8F8 Q6S991 ENST00000396211.7 [P41586-2] ENST00000304166.9 [P41586-1] E9PFU5 Q6RKA2 ENST00000409489.5 A0A994J7E9 ENST00000705424.1 [P41586-2] Q6RKA3 ENST00000705423.1 C9JVH3 |
