Insufficient scRNA-seq data for expression of TBXA2R at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 957.44 | 258 / 258 | 97% | 13.04 | 224 / 230 |
| thymus | 91% | 347.99 | 593 / 653 | 97% | 5.30 | 589 / 605 |
| lung | 98% | 545.40 | 564 / 578 | 90% | 2.87 | 1035 / 1155 |
| liver | 95% | 386.66 | 215 / 226 | 89% | 3.21 | 360 / 406 |
| kidney | 98% | 614.90 | 87 / 89 | 84% | 7.57 | 756 / 901 |
| esophagus | 84% | 488.19 | 1221 / 1445 | 93% | 3.42 | 170 / 183 |
| intestine | 88% | 287.67 | 850 / 966 | 87% | 2.57 | 457 / 527 |
| prostate | 90% | 320.67 | 220 / 245 | 83% | 2.06 | 418 / 502 |
| uterus | 97% | 562.68 | 165 / 170 | 74% | 3.18 | 338 / 459 |
| breast | 71% | 220.88 | 325 / 459 | 97% | 3.54 | 1086 / 1118 |
| bladder | 86% | 291.19 | 18 / 21 | 81% | 2.57 | 406 / 504 |
| stomach | 72% | 226.76 | 259 / 359 | 87% | 3.60 | 249 / 286 |
| ovary | 60% | 204.23 | 108 / 180 | 82% | 2.26 | 352 / 430 |
| skin | 41% | 93.66 | 737 / 1809 | 93% | 10.84 | 440 / 472 |
| brain | 9% | 14.67 | 243 / 2642 | 96% | 4.33 | 676 / 705 |
| pancreas | 6% | 10.16 | 19 / 328 | 98% | 3.93 | 175 / 178 |
| blood vessel | 100% | 3680.82 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 2.57 | 29 / 29 |
| spleen | 100% | 850.94 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.63 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 95% | 3.33 | 76 / 80 |
| adipose | 93% | 464.28 | 1125 / 1204 | 0% | 0 | 0 / 0 |
| heart | 84% | 224.91 | 722 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 71% | 1.39 | 32 / 45 |
| peripheral blood | 37% | 84.25 | 348 / 929 | 0% | 0 | 0 / 0 |
| muscle | 8% | 16.53 | 67 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007584 | Biological process | response to nutrient |
| GO_0033574 | Biological process | response to testosterone |
| GO_0006939 | Biological process | smooth muscle contraction |
| GO_0090051 | Biological process | negative regulation of cell migration involved in sprouting angiogenesis |
| GO_0006954 | Biological process | inflammatory response |
| GO_0045777 | Biological process | positive regulation of blood pressure |
| GO_0045766 | Biological process | positive regulation of angiogenesis |
| GO_0045907 | Biological process | positive regulation of vasoconstriction |
| GO_0045471 | Biological process | response to ethanol |
| GO_0045987 | Biological process | positive regulation of smooth muscle contraction |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0030194 | Biological process | positive regulation of blood coagulation |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0038193 | Biological process | thromboxane A2 signaling pathway |
| GO_0001669 | Cellular component | acrosomal vesicle |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004961 | Molecular function | thromboxane A2 receptor activity |
| Gene name | TBXA2R |
| Protein name | Thromboxane A2 receptor (Prostanoid TP receptor) Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor) TBXA2R protein |
| Synonyms | |
| Description | FUNCTION: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. .; FUNCTION: [Isoform 1]: Activates adenylyl cyclase. .; FUNCTION: [Isoform 2]: Inhibits adenylyl cyclase. . |
| Accessions | ENST00000589966.1 Q0VAB0 P21731 Q0VAA9 K7ER80 ENST00000411851.3 [P21731-2] ENST00000375190.10 [P21731-3] Q05C92 |
