Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 38 studies | 47% ± 17% | |
endothelial cell | 34 studies | 33% ± 12% | |
fibroblast | 30 studies | 31% ± 11% | |
smooth muscle cell | 24 studies | 41% ± 14% | |
endothelial cell of lymphatic vessel | 16 studies | 26% ± 10% | |
connective tissue cell | 9 studies | 31% ± 19% | |
mesothelial cell | 9 studies | 46% ± 18% | |
endothelial cell of artery | 8 studies | 27% ± 11% | |
capillary endothelial cell | 8 studies | 25% ± 7% | |
vein endothelial cell | 6 studies | 23% ± 6% | |
epithelial cell | 6 studies | 35% ± 21% | |
oligodendrocyte | 5 studies | 29% ± 8% | |
Mueller cell | 5 studies | 28% ± 7% | |
endothelial cell of vascular tree | 5 studies | 32% ± 11% | |
hepatocyte | 5 studies | 74% ± 13% | |
kidney connecting tubule epithelial cell | 4 studies | 56% ± 22% | |
abnormal cell | 4 studies | 37% ± 17% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 46% ± 15% | |
kidney loop of Henle epithelial cell | 4 studies | 39% ± 11% | |
basal cell | 4 studies | 28% ± 12% | |
glial cell | 4 studies | 41% ± 21% | |
myofibroblast cell | 4 studies | 36% ± 23% | |
mast cell | 4 studies | 16% ± 0% | |
epithelial cell of proximal tubule | 4 studies | 29% ± 8% | |
renal principal cell | 4 studies | 40% ± 13% | |
neuron | 3 studies | 29% ± 8% | |
cholangiocyte | 3 studies | 61% ± 15% | |
muscle cell | 3 studies | 57% ± 7% | |
Schwann cell | 3 studies | 41% ± 13% | |
secretory cell | 3 studies | 38% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 41585.95 | 180 / 180 | 99% | 119.10 | 425 / 430 |
liver | 100% | 39845.27 | 226 / 226 | 99% | 206.73 | 401 / 406 |
kidney | 100% | 27865.22 | 89 / 89 | 96% | 122.43 | 864 / 901 |
thymus | 100% | 18599.31 | 652 / 653 | 95% | 68.84 | 573 / 605 |
esophagus | 96% | 10050.35 | 1393 / 1445 | 96% | 72.93 | 175 / 183 |
pancreas | 96% | 9329.94 | 316 / 328 | 94% | 92.39 | 167 / 178 |
breast | 100% | 17404.92 | 459 / 459 | 90% | 65.29 | 1003 / 1118 |
lung | 99% | 14101.58 | 575 / 578 | 86% | 58.21 | 999 / 1155 |
adrenal gland | 100% | 12506.50 | 258 / 258 | 85% | 61.50 | 195 / 230 |
uterus | 100% | 22174.29 | 170 / 170 | 79% | 61.88 | 363 / 459 |
skin | 86% | 9686.41 | 1549 / 1809 | 92% | 81.75 | 434 / 472 |
prostate | 100% | 14466.96 | 244 / 245 | 77% | 28.86 | 387 / 502 |
intestine | 95% | 12307.50 | 914 / 966 | 77% | 42.53 | 406 / 527 |
bladder | 100% | 18483.19 | 21 / 21 | 69% | 37.77 | 350 / 504 |
stomach | 71% | 5693.14 | 254 / 359 | 81% | 56.21 | 233 / 286 |
adipose | 100% | 22164.11 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 70655.26 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 12727.05 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 94% | 11289.92 | 812 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 62.60 | 72 / 80 |
tonsil | 0% | 0 | 0 / 0 | 78% | 48.96 | 35 / 45 |
brain | 22% | 1606.40 | 575 / 2642 | 44% | 18.46 | 308 / 705 |
lymph node | 0% | 0 | 0 / 0 | 62% | 22.36 | 18 / 29 |
peripheral blood | 41% | 3505.38 | 382 / 929 | 0% | 0 | 0 / 0 |
muscle | 21% | 1188.29 | 170 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007601 | Biological process | visual perception |
GO_0001525 | Biological process | angiogenesis |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0009887 | Biological process | animal organ morphogenesis |
GO_0051599 | Biological process | response to hydrostatic pressure |
GO_0007155 | Biological process | cell adhesion |
GO_0001501 | Biological process | skeletal system development |
GO_0030199 | Biological process | collagen fibril organization |
GO_0001886 | Biological process | endothelial cell morphogenesis |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0030903 | Biological process | notochord development |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005581 | Cellular component | collagen trimer |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005604 | Cellular component | basement membrane |
GO_0030020 | Molecular function | extracellular matrix structural constituent conferring tensile strength |
GO_0046872 | Molecular function | metal ion binding |
Gene name | COL18A1 |
Protein name | Alternative protein COL18A1 Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)] Collagen alpha-1(XVIII) chain isoform 1 preproprotein Collagen type XVIII alpha 1 chain |
Synonyms | |
Description | FUNCTION: Probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. .; FUNCTION: [Non-collagenous domain 1]: May regulate extracellular matrix-dependent motility and morphogenesis of endothelial and non-endothelial cells; the function requires homotrimerization and implicates MAPK signaling. .; FUNCTION: [Endostatin]: Potently inhibits endothelial cell proliferation and angiogenesis . May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling (By similarity). Inhibits VEGFA-induced endothelial cell proliferation and migration. Seems to inhibit VEGFA-mediated signaling by blocking the interaction of VEGFA to its receptor KDR/VEGFR2. Modulates endothelial cell migration in an integrin-dependent manner implicating integrin ITGA5:ITGB1 and to a lesser extent ITGAV:ITGB3 and ITGAV:ITGB5 (By similarity). May negatively regulate the activity of homotrimeric non-collagenous domain 1 . . |
Accessions | A0A1B1PFY7 ENST00000651438.1 [P39060-2] H7BXV5 H7C457 ENST00000423214.1 L8ECK6 ENST00000342220.9 P39060 ENST00000359759.8 [P39060-3] ENST00000355480.10 [P39060-1] |