TXN2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	19 studies	23% ± 6%	Explore
conventional dendritic cell	19 studies	27% ± 15%	Explore
B cell	17 studies	22% ± 7%	Explore
CD8-positive, alpha-beta T cell	15 studies	26% ± 8%	Explore
endothelial cell	15 studies	27% ± 12%	Explore
fibroblast	15 studies	29% ± 12%	Explore
macrophage	14 studies	25% ± 8%	Explore
CD4-positive, alpha-beta T cell	13 studies	26% ± 10%	Explore
regulatory T cell	13 studies	23% ± 8%	Explore
T cell	12 studies	20% ± 4%	Explore
non-classical monocyte	12 studies	30% ± 13%	Explore
classical monocyte	12 studies	27% ± 10%	Explore
smooth muscle cell	11 studies	24% ± 6%	Explore
basal cell	10 studies	30% ± 16%	Explore
monocyte	10 studies	25% ± 9%	Explore
memory B cell	10 studies	20% ± 5%	Explore
plasmacytoid dendritic cell	10 studies	27% ± 8%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	23% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	24% ± 8%	Explore
connective tissue cell	9 studies	28% ± 9%	Explore
epithelial cell	9 studies	41% ± 21%	Explore
gamma-delta T cell	9 studies	24% ± 15%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	22% ± 4%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	20% ± 4%	Explore
abnormal cell	8 studies	25% ± 15%	Explore
plasma cell	7 studies	30% ± 12%	Explore
myofibroblast cell	7 studies	27% ± 4%	Explore
pericyte	7 studies	27% ± 8%	Explore
dendritic cell	7 studies	38% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	24% ± 8%	Explore
mature NK T cell	6 studies	20% ± 3%	Explore
progenitor cell	6 studies	25% ± 3%	Explore
enterocyte	6 studies	22% ± 3%	Explore
endothelial cell of vascular tree	6 studies	20% ± 3%	Explore
myeloid cell	6 studies	26% ± 10%	Explore
ciliated cell	6 studies	34% ± 11%	Explore
mucosal invariant T cell	6 studies	18% ± 3%	Explore
hematopoietic precursor cell	5 studies	37% ± 17%	Explore
plasmablast	5 studies	43% ± 20%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	22% ± 3%	Explore
kidney loop of Henle epithelial cell	5 studies	26% ± 6%	Explore
epithelial cell of proximal tubule	5 studies	23% ± 2%	Explore
endothelial cell of artery	5 studies	19% ± 5%	Explore
goblet cell	5 studies	24% ± 10%	Explore
intestinal crypt stem cell	5 studies	25% ± 6%	Explore
mesothelial cell	5 studies	32% ± 17%	Explore
transit amplifying cell	5 studies	22% ± 6%	Explore
erythroblast	5 studies	36% ± 14%	Explore
hematopoietic stem cell	5 studies	22% ± 6%	Explore
erythrocyte	5 studies	32% ± 19%	Explore
exhausted T cell	4 studies	29% ± 7%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	30% ± 7%	Explore
naive B cell	4 studies	20% ± 5%	Explore
retinal ganglion cell	4 studies	50% ± 28%	Explore
amacrine cell	4 studies	37% ± 16%	Explore
T follicular helper cell	4 studies	19% ± 2%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	30% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	32% ± 6%	Explore
neuron	4 studies	31% ± 16%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	25% ± 8%	Explore
enteroendocrine cell	4 studies	29% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	4 studies	27% ± 11%	Explore
mononuclear phagocyte	3 studies	33% ± 17%	Explore
renal alpha-intercalated cell	3 studies	28% ± 2%	Explore
leukocyte	3 studies	29% ± 8%	Explore
neural crest cell	3 studies	29% ± 3%	Explore
vein endothelial cell	3 studies	21% ± 4%	Explore
retinal bipolar neuron	3 studies	39% ± 12%	Explore
common myeloid progenitor	3 studies	31% ± 17%	Explore
innate lymphoid cell	3 studies	20% ± 1%	Explore
club cell	3 studies	24% ± 9%	Explore
capillary endothelial cell	3 studies	22% ± 5%	Explore
endothelial cell of lymphatic vessel	3 studies	28% ± 8%	Explore
precursor B cell	3 studies	18% ± 3%	Explore
type I pneumocyte	3 studies	26% ± 10%	Explore
type II pneumocyte	3 studies	33% ± 15%	Explore
astrocyte	3 studies	27% ± 14%	Explore
retina horizontal cell	3 studies	38% ± 12%	Explore
Mueller cell	3 studies	30% ± 9%	Explore
germinal center B cell	3 studies	24% ± 1%	Explore
intermediate monocyte	3 studies	35% ± 14%	Explore
myoepithelial cell	3 studies	25% ± 6%	Explore
oligodendrocyte precursor cell	3 studies	29% ± 7%	Explore
granulocyte monocyte progenitor cell	3 studies	35% ± 20%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	43% ± 24%	Explore
mast cell	3 studies	18% ± 3%	Explore
double negative thymocyte	3 studies	32% ± 19%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	21% ± 2%	Explore
progenitor cell of mammary luminal epithelium	3 studies	19% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	11 studies	25% ± 7%	Explore
intestine	8 studies	25% ± 11%	Explore
kidney	7 studies	20% ± 3%	Explore
lung	7 studies	31% ± 11%	Explore
eye	6 studies	24% ± 8%	Explore
bone marrow	4 studies	17% ± 1%	Explore
liver	4 studies	31% ± 20%	Explore
lymph node	3 studies	24% ± 11%	Explore
brain	3 studies	23% ± 2%	Explore
breast	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	10646.03	258 / 258	100%	174.37	230 / 230
esophagus	100%	3723.48	1445 / 1445	100%	95.64	183 / 183
intestine	100%	3596.98	966 / 966	100%	158.06	527 / 527
liver	100%	4777.58	226 / 226	100%	163.14	406 / 406
ovary	100%	4035.48	180 / 180	100%	131.13	430 / 430
pancreas	100%	2045.31	328 / 328	100%	127.09	178 / 178
skin	100%	3966.25	1809 / 1809	100%	213.70	472 / 472
thymus	100%	4231.71	653 / 653	100%	190.83	605 / 605
brain	100%	3719.31	2640 / 2642	100%	242.16	705 / 705
kidney	100%	5002.87	89 / 89	100%	160.14	900 / 901
prostate	100%	3849.31	245 / 245	100%	197.07	501 / 502
stomach	100%	3691.81	359 / 359	100%	137.16	285 / 286
bladder	100%	3729.90	21 / 21	100%	169.80	502 / 504
uterus	100%	3268.27	170 / 170	100%	159.93	457 / 459
lung	100%	2992.11	576 / 578	99%	143.47	1146 / 1155
breast	100%	3678.12	459 / 459	99%	153.72	1104 / 1118
adipose	100%	3553.16	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	271.71	80 / 80
lymph node	0%	0	0 / 0	100%	260.34	29 / 29
muscle	100%	5197.50	803 / 803	0%	0	0 / 0
spleen	100%	4057.34	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	147.42	45 / 45
ureter	0%	0	0 / 0	100%	120.05	1 / 1
blood vessel	100%	2798.94	1332 / 1335	0%	0	0 / 0
heart	99%	4462.51	854 / 861	0%	0	0 / 0
peripheral blood	98%	3169.94	906 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045454	Biological process	cell redox homeostasis
GO_0009749	Biological process	response to glucose
GO_0048678	Biological process	response to axon injury
GO_0014070	Biological process	response to organic cyclic compound
GO_0031669	Biological process	cellular response to nutrient levels
GO_0009725	Biological process	response to hormone
GO_0001666	Biological process	response to hypoxia
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0006979	Biological process	response to oxidative stress
GO_0005730	Cellular component	nucleolus
GO_0005739	Cellular component	mitochondrion
GO_0043025	Cellular component	neuronal cell body
GO_0030425	Cellular component	dendrite
GO_0005759	Cellular component	mitochondrial matrix
GO_0008113	Molecular function	peptide-methionine (S)-S-oxide reductase activity
GO_0044877	Molecular function	protein-containing complex binding
GO_0015035	Molecular function	protein-disulfide reductase activity
GO_0033743	Molecular function	peptide-methionine (R)-S-oxide reductase activity
GO_0005515	Molecular function	protein binding

Gene name	TXN2
Protein name	Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2) Thioredoxin 2
Synonyms	TRX2
Description	FUNCTION: Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity. .
Accessions	ENST00000411915.1 M0QXH0 Q99757 ENST00000216185.7 ENST00000416967.1 ENST00000403313.5 F8WDN2

TXN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review