Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 32% ± 11% | |
| hepatocyte | 3 studies | 43% ± 20% | |
| GABAergic neuron | 3 studies | 29% ± 7% | |
| dendritic cell | 3 studies | 19% ± 3% | |
| interneuron | 3 studies | 26% ± 10% | |
| neuron | 3 studies | 18% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 25% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 1657.14 | 2599 / 2642 | 100% | 16.30 | 703 / 705 |
| liver | 100% | 3804.18 | 226 / 226 | 97% | 16.44 | 393 / 406 |
| kidney | 99% | 973.71 | 88 / 89 | 97% | 12.09 | 875 / 901 |
| skin | 100% | 3314.53 | 1804 / 1809 | 96% | 9.78 | 454 / 472 |
| ovary | 97% | 807.38 | 174 / 180 | 98% | 10.37 | 422 / 430 |
| uterus | 96% | 680.41 | 163 / 170 | 98% | 17.47 | 452 / 459 |
| lung | 88% | 565.41 | 510 / 578 | 98% | 15.45 | 1134 / 1155 |
| breast | 89% | 579.59 | 409 / 459 | 95% | 13.00 | 1065 / 1118 |
| intestine | 84% | 645.51 | 809 / 966 | 99% | 12.09 | 521 / 527 |
| pancreas | 85% | 502.77 | 278 / 328 | 98% | 10.68 | 174 / 178 |
| stomach | 82% | 494.01 | 296 / 359 | 99% | 11.48 | 282 / 286 |
| prostate | 84% | 479.11 | 207 / 245 | 95% | 6.80 | 479 / 502 |
| esophagus | 76% | 2011.47 | 1092 / 1445 | 99% | 19.16 | 181 / 183 |
| adrenal gland | 83% | 453.35 | 213 / 258 | 90% | 15.85 | 206 / 230 |
| bladder | 76% | 387.10 | 16 / 21 | 94% | 11.59 | 476 / 504 |
| thymus | 64% | 293.35 | 419 / 653 | 68% | 3.50 | 414 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 25.33 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.63 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 10.37 | 79 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 6.14 | 26 / 29 |
| blood vessel | 87% | 536.31 | 1168 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 85% | 428.64 | 206 / 241 | 0% | 0 | 0 / 0 |
| adipose | 79% | 450.12 | 949 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 55% | 519.00 | 512 / 929 | 0% | 0 | 0 / 0 |
| heart | 17% | 71.98 | 144 / 861 | 0% | 0 | 0 / 0 |
| muscle | 4% | 17.50 | 33 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0021794 | Biological process | thalamus development |
| GO_0021766 | Biological process | hippocampus development |
| GO_0071549 | Biological process | cellular response to dexamethasone stimulus |
| GO_0030540 | Biological process | female genitalia development |
| GO_0032869 | Biological process | cellular response to insulin stimulus |
| GO_0021510 | Biological process | spinal cord development |
| GO_0043627 | Biological process | response to estrogen |
| GO_0001655 | Biological process | urogenital system development |
| GO_0042448 | Biological process | progesterone metabolic process |
| GO_0071392 | Biological process | cellular response to estradiol stimulus |
| GO_0071872 | Biological process | cellular response to epinephrine stimulus |
| GO_0001889 | Biological process | liver development |
| GO_0071394 | Biological process | cellular response to testosterone stimulus |
| GO_0009267 | Biological process | cellular response to starvation |
| GO_0071363 | Biological process | cellular response to growth factor stimulus |
| GO_0006694 | Biological process | steroid biosynthetic process |
| GO_0014850 | Biological process | response to muscle activity |
| GO_0060416 | Biological process | response to growth hormone |
| GO_0032354 | Biological process | response to follicle-stimulating hormone |
| GO_0071320 | Biological process | cellular response to cAMP |
| GO_0030539 | Biological process | male genitalia development |
| GO_0060992 | Biological process | response to fungicide |
| GO_0030154 | Biological process | cell differentiation |
| GO_0006702 | Biological process | androgen biosynthetic process |
| GO_0008584 | Biological process | male gonad development |
| GO_0021987 | Biological process | cerebral cortex development |
| GO_0021983 | Biological process | pituitary gland development |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0006710 | Biological process | androgen catabolic process |
| GO_0060348 | Biological process | bone development |
| GO_0042428 | Biological process | serotonin metabolic process |
| GO_0016101 | Biological process | diterpenoid metabolic process |
| GO_0007530 | Biological process | sex determination |
| GO_0021854 | Biological process | hypothalamus development |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0070852 | Cellular component | cell body fiber |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0009055 | Molecular function | electron transfer activity |
| GO_0003865 | Molecular function | 3-oxo-5-alpha-steroid 4-dehydrogenase activity |
| GO_0070402 | Molecular function | NADPH binding |
| GO_0033218 | Molecular function | amide binding |
| GO_0047751 | Molecular function | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity |
| Gene name | SRD5A1 |
| Protein name | Steroid 5 alpha-reductase 1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1) |
| Synonyms | |
| Description | FUNCTION: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. . |
| Accessions | D6RG03 D6RDL6 P18405 ENST00000510531.5 ENST00000513117.1 ENST00000274192.7 |
