Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| erythroblast | 4 studies | 41% ± 22% | |
| erythrocyte | 4 studies | 40% ± 19% | |
| glutamatergic neuron | 4 studies | 24% ± 9% | |
| epithelial cell | 3 studies | 26% ± 8% | |
| astrocyte | 3 studies | 26% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 21% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 25268.66 | 258 / 258 | 100% | 72.73 | 230 / 230 |
| stomach | 100% | 6393.81 | 359 / 359 | 100% | 32.94 | 286 / 286 |
| esophagus | 100% | 3857.94 | 1443 / 1445 | 100% | 28.86 | 183 / 183 |
| brain | 100% | 8257.29 | 2642 / 2642 | 100% | 65.17 | 704 / 705 |
| liver | 100% | 8426.13 | 226 / 226 | 100% | 104.22 | 405 / 406 |
| ovary | 100% | 4684.08 | 180 / 180 | 100% | 24.35 | 428 / 430 |
| thymus | 100% | 4171.94 | 653 / 653 | 100% | 49.40 | 602 / 605 |
| skin | 100% | 4308.50 | 1807 / 1809 | 100% | 38.71 | 470 / 472 |
| intestine | 100% | 3959.25 | 966 / 966 | 99% | 33.69 | 524 / 527 |
| breast | 100% | 3782.83 | 459 / 459 | 99% | 48.95 | 1111 / 1118 |
| pancreas | 99% | 4381.31 | 326 / 328 | 99% | 43.05 | 177 / 178 |
| uterus | 100% | 3303.18 | 170 / 170 | 99% | 30.14 | 453 / 459 |
| lung | 99% | 2804.24 | 571 / 578 | 100% | 31.84 | 1152 / 1155 |
| prostate | 100% | 4733.07 | 244 / 245 | 99% | 37.66 | 496 / 502 |
| kidney | 100% | 4685.44 | 89 / 89 | 98% | 34.45 | 884 / 901 |
| bladder | 100% | 3423.19 | 21 / 21 | 98% | 27.74 | 492 / 504 |
| adipose | 100% | 3702.31 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2325.44 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 29.96 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.46 | 1 / 1 |
| blood vessel | 100% | 3407.96 | 1330 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 31.46 | 79 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 22.97 | 28 / 29 |
| muscle | 94% | 1854.41 | 756 / 803 | 0% | 0 | 0 / 0 |
| heart | 94% | 4255.73 | 809 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 78% | 1417.95 | 729 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051260 | Biological process | protein homooligomerization |
| GO_0010039 | Biological process | response to iron ion |
| GO_0043200 | Biological process | response to amino acid |
| GO_0070542 | Biological process | response to fatty acid |
| GO_0010212 | Biological process | response to ionizing radiation |
| GO_0010044 | Biological process | response to aluminum ion |
| GO_0006783 | Biological process | heme biosynthetic process |
| GO_0006784 | Biological process | heme A biosynthetic process |
| GO_0046685 | Biological process | response to arsenic-containing substance |
| GO_0010266 | Biological process | response to vitamin B1 |
| GO_0014823 | Biological process | response to activity |
| GO_0045471 | Biological process | response to ethanol |
| GO_0071353 | Biological process | cellular response to interleukin-4 |
| GO_1901799 | Biological process | negative regulation of proteasomal protein catabolic process |
| GO_0033197 | Biological process | response to vitamin E |
| GO_0006785 | Biological process | heme B biosynthetic process |
| GO_0070541 | Biological process | response to platinum ion |
| GO_0046686 | Biological process | response to cadmium ion |
| GO_0051384 | Biological process | response to glucocorticoid |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0009635 | Biological process | response to herbicide |
| GO_0010043 | Biological process | response to zinc ion |
| GO_0006782 | Biological process | protoporphyrinogen IX biosynthetic process |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0032025 | Biological process | response to cobalt ion |
| GO_0010269 | Biological process | response to selenium ion |
| GO_0046689 | Biological process | response to mercury ion |
| GO_0006979 | Biological process | response to oxidative stress |
| GO_0051597 | Biological process | response to methylmercury |
| GO_0048034 | Biological process | heme O biosynthetic process |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0071284 | Biological process | cellular response to lead ion |
| GO_0005576 | Cellular component | extracellular region |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0034774 | Cellular component | secretory granule lumen |
| GO_1904813 | Cellular component | ficolin-1-rich granule lumen |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_1904854 | Molecular function | proteasome core complex binding |
| GO_0003824 | Molecular function | catalytic activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0004655 | Molecular function | porphobilinogen synthase activity |
| Gene name | ALAD |
| Protein name | Aminolevulinate dehydratase porphobilinogen synthase (EC 4.2.1.24) (Porphobilinogen synthase) Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase) |
| Synonyms | |
| Description | FUNCTION: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. . FUNCTION: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. . FUNCTION: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. . |
| Accessions | ENST00000448137.5 ENST00000445750.1 B7ZBK6 ENST00000452726.1 B7ZBK8 ENST00000409155.8 [P13716-1] B7ZBK7 P13716 |
