Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hepatocyte | 6 studies | 80% ± 12% | |
| enterocyte | 5 studies | 34% ± 15% | |
| intestinal crypt stem cell | 3 studies | 33% ± 14% | |
| glutamatergic neuron | 3 studies | 23% ± 5% | |
| epithelial cell | 3 studies | 32% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 4 studies | 49% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 87074.35 | 226 / 226 | 86% | 336.88 | 351 / 406 |
| brain | 93% | 471.27 | 2470 / 2642 | 79% | 5.97 | 554 / 705 |
| skin | 98% | 877.85 | 1764 / 1809 | 63% | 5.89 | 298 / 472 |
| esophagus | 92% | 225.28 | 1327 / 1445 | 36% | 24.33 | 65 / 183 |
| lung | 95% | 275.96 | 550 / 578 | 30% | 39.05 | 344 / 1155 |
| breast | 99% | 380.49 | 456 / 459 | 18% | 1.21 | 204 / 1118 |
| uterus | 98% | 381.35 | 167 / 170 | 18% | 5.17 | 82 / 459 |
| thymus | 99% | 325.47 | 644 / 653 | 16% | 0.65 | 96 / 605 |
| kidney | 94% | 254.08 | 84 / 89 | 19% | 2.11 | 173 / 901 |
| ovary | 100% | 573.19 | 180 / 180 | 11% | 0.91 | 46 / 430 |
| intestine | 82% | 1444.20 | 793 / 966 | 28% | 10.72 | 150 / 527 |
| bladder | 86% | 163.38 | 18 / 21 | 14% | 7.42 | 73 / 504 |
| blood vessel | 98% | 349.52 | 1310 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 98% | 310.76 | 1176 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 97% | 310.85 | 233 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 70% | 100.23 | 228 / 328 | 27% | 6.75 | 48 / 178 |
| prostate | 86% | 206.11 | 210 / 245 | 11% | 2.77 | 54 / 502 |
| stomach | 49% | 104.97 | 176 / 359 | 40% | 29.92 | 115 / 286 |
| heart | 86% | 183.54 | 737 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 65% | 82.47 | 168 / 258 | 7% | 0.35 | 17 / 230 |
| muscle | 42% | 53.51 | 334 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 35% | 2.63 | 28 / 80 |
| peripheral blood | 19% | 67.53 | 181 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.57 | 4 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.07 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0014075 | Biological process | response to amine |
| GO_0043200 | Biological process | response to amino acid |
| GO_0070409 | Biological process | carbamoyl phosphate biosynthetic process |
| GO_0007494 | Biological process | midgut development |
| GO_0006541 | Biological process | glutamine metabolic process |
| GO_0055081 | Biological process | monoatomic anion homeostasis |
| GO_0042594 | Biological process | response to starvation |
| GO_0006207 | Biological process | 'de novo' pyrimidine nucleobase biosynthetic process |
| GO_0060416 | Biological process | response to growth hormone |
| GO_0019433 | Biological process | triglyceride catabolic process |
| GO_0071548 | Biological process | response to dexamethasone |
| GO_0071320 | Biological process | cellular response to cAMP |
| GO_0000050 | Biological process | urea cycle |
| GO_0071377 | Biological process | cellular response to glucagon stimulus |
| GO_0010043 | Biological process | response to zinc ion |
| GO_0050667 | Biological process | homocysteine metabolic process |
| GO_0071242 | Biological process | cellular response to ammonium ion |
| GO_0071400 | Biological process | cellular response to oleic acid |
| GO_0046209 | Biological process | nitric oxide metabolic process |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0009636 | Biological process | response to toxic substance |
| GO_0032094 | Biological process | response to food |
| GO_0042311 | Biological process | vasodilation |
| GO_0070365 | Biological process | hepatocyte differentiation |
| GO_0044344 | Biological process | cellular response to fibroblast growth factor stimulus |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0019240 | Biological process | citrulline biosynthetic process |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0042645 | Cellular component | mitochondrial nucleoid |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004088 | Molecular function | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity |
| GO_0004175 | Molecular function | endopeptidase activity |
| GO_0005543 | Molecular function | phospholipid binding |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0004087 | Molecular function | carbamoyl-phosphate synthase (ammonia) activity |
| GO_0016595 | Molecular function | glutamate binding |
| GO_0036094 | Molecular function | small molecule binding |
| GO_0030955 | Molecular function | potassium ion binding |
| GO_0072341 | Molecular function | modified amino acid binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CPS1 |
| Protein name | carbamoyl-phosphate synthase (ammonia) (EC 6.3.4.16) CPS1 protein carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC 6.3.5.5) Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I) |
| Synonyms | |
| Description | FUNCTION: Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. |
| Accessions | ENST00000233072.10 [P31327-1] Q5R206 Q5R210 ENST00000673630.1 [P31327-1] ENST00000430249.7 [P31327-3] Q5R208 ENST00000673711.1 [P31327-1] Q5R211 ENST00000451903.3 [P31327-2] ENST00000673510.1 [P31327-1] Q05CV6 Q5R209 P31327 ENST00000673698.1 A0A669KBF2 Q5R207 |
