I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| mesothelial cell | 5 studies | 23% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| mesothelial cell | 5 studies | 23% ± 12% |
Insufficient scRNA-seq data for expression of CA9 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 92% | 12615.75 | 331 / 359 | 47% | 52.37 | 135 / 286 |
| pancreas | 72% | 244.09 | 237 / 328 | 63% | 173.53 | 112 / 178 |
| intestine | 56% | 78.57 | 544 / 966 | 57% | 100.71 | 300 / 527 |
| esophagus | 57% | 76.33 | 826 / 1445 | 45% | 46.54 | 83 / 183 |
| bladder | 38% | 75.38 | 8 / 21 | 49% | 71.37 | 245 / 504 |
| uterus | 23% | 22.38 | 39 / 170 | 61% | 116.86 | 278 / 459 |
| skin | 77% | 316.65 | 1401 / 1809 | 4% | 2.48 | 19 / 472 |
| kidney | 7% | 11.82 | 6 / 89 | 64% | 260.88 | 575 / 901 |
| ovary | 23% | 34.64 | 42 / 180 | 38% | 26.68 | 162 / 430 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 60.98 | 27 / 45 |
| liver | 31% | 41.52 | 70 / 226 | 21% | 60.90 | 84 / 406 |
| lung | 6% | 12.51 | 34 / 578 | 45% | 60.60 | 519 / 1155 |
| blood vessel | 50% | 115.29 | 673 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 36% | 50.58 | 87 / 245 | 0% | 0 | 0 / 502 |
| brain | 20% | 195.66 | 533 / 2642 | 14% | 10.93 | 99 / 705 |
| adipose | 30% | 108.22 | 362 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 15% | 21.87 | 38 / 258 | 9% | 13.41 | 21 / 230 |
| heart | 21% | 53.49 | 179 / 861 | 0% | 0 | 0 / 0 |
| breast | 3% | 4.41 | 15 / 459 | 13% | 11.63 | 148 / 1118 |
| peripheral blood | 4% | 7.16 | 40 / 929 | 0% | 0 | 0 / 0 |
| muscle | 3% | 2.13 | 24 / 803 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0.33 | 3 / 653 | 1% | 1.09 | 7 / 605 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0033574 | Biological process | response to testosterone |
| GO_0046903 | Biological process | secretion |
| GO_0006730 | Biological process | one-carbon metabolic process |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0002009 | Biological process | morphogenesis of an epithelium |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0031528 | Cellular component | microvillus membrane |
| GO_0140677 | Molecular function | molecular function activator activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0004089 | Molecular function | carbonate dehydratase activity |
| Gene name | CA9 |
| Protein name | Carbonic anhydrase 9 (EC 4.2.1.1) (Carbonate dehydratase IX) (Carbonic anhydrase IX) (CA-IX) (CAIX) (Membrane antigen MN) (P54/58N) (Renal cell carcinoma-associated antigen G250) (RCC-associated antigen G250) (pMW1) Carbonic anhydrase (EC 4.2.1.1) |
| Synonyms | G250 MN |
| Description | FUNCTION: Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). . FUNCTION: Reversible hydration of carbon dioxide. . FUNCTION: Reversible hydration of carbon dioxide. . |
| Accessions | A0A0S2Z3D0 Q16790 A0A0S2Z341 ENST00000378357.9 |
