NFATC2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0014904Biological processmyotube cell development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0010628Biological processpositive regulation of gene expression
GO_0006974Biological processDNA damage response
GO_0050853Biological processB cell receptor signaling pathway
GO_0001816Biological processcytokine production
GO_0033173Biological processcalcineurin-NFAT signaling cascade
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_1905064Biological processnegative regulation of vascular associated smooth muscle cell differentiation
GO_0071277Biological processcellular response to calcium ion
GO_1901741Biological processpositive regulation of myoblast fusion
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0030890Biological processpositive regulation of B cell proliferation
GO_0006355Biological processregulation of DNA-templated transcription
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0051216Biological processcartilage development
GO_0016477Biological processcell migration
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0035976Cellular componenttranscription factor AP-1 complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_1990904Cellular componentribonucleoprotein complex
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0008134Molecular functiontranscription factor binding
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0060090Molecular functionmolecular adaptor activity
GO_0003682Molecular functionchromatin binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0071889Molecular function14-3-3 protein binding
GO_0019902Molecular functionphosphatase binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNFATC2
Protein nameNuclear factor of activated T-cells c2 isoform IA-IIS-deltaXa (Nuclear factor of activated T-cells c2 isoform IB-IIS-deltaXa)
Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2) (NFATc2) (NFAT pre-existing subunit) (NF-ATp) (T-cell transcription factor NFAT1)
SynonymsNFAT1
NFATP
DescriptionFUNCTION: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF . Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway . Is involved in the negative regulation of chondrogenesis . .

AccessionsENST00000609943.5 [Q13469-4]
ENST00000396009.7 [Q13469-1]
ENST00000610033.5 [Q13469-5]
B5B2P4
ENST00000371564.8 [Q13469-2]
Q13469
ENST00000609507.1 [Q13469-5]
ENST00000414705.5 [Q13469-3]