transcription factor AP-1 complex

I. Literature review

[source]
Nametranscription factor AP-1 complex
IDGO_0035976
collection_id

Cellular component

Exact synonym

AP-1 complex, AP1 complex, Activating protein 1 complex, transcription factor AP1 complex

Description

A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.

External URL
Genes
FOSJUNJUNBNFATC2JUND