JUNB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0033687Biological processosteoblast proliferation
GO_0060136Biological processembryonic process involved in female pregnancy
GO_0030316Biological processosteoclast differentiation
GO_0046697Biological processdecidualization
GO_0001649Biological processosteoblast differentiation
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0001829Biological processtrophectodermal cell differentiation
GO_0001570Biological processvasculogenesis
GO_0071277Biological processcellular response to calcium ion
GO_0045597Biological processpositive regulation of cell differentiation
GO_0060716Biological processlabyrinthine layer blood vessel development
GO_0002158Biological processosteoclast proliferation
GO_2000319Biological processregulation of T-helper 17 cell differentiation
GO_0042127Biological processregulation of cell population proliferation
GO_0051726Biological processregulation of cell cycle
GO_0140467Biological processintegrated stress response signaling
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0035976Cellular componenttranscription factor AP-1 complex
GO_0005654Cellular componentnucleoplasm
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0008134Molecular functiontranscription factor binding
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameJUNB
Protein nameTranscription factor JunB (Transcription factor AP-1 subunit JunB)
Ribonuclease (EC 3.1.26.4)
SynonymshCG_172481
DescriptionFUNCTION: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[GC]TCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity (By similarity). .

FUNCTION: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. .; FUNCTION: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. .

AccessionsP17275
Q5U079
ENST00000302754.6
Q6IBG3