Name | Number of supported studies | Average coverage | |
---|---|---|---|
plasmablast | 6 studies | 48% ± 22% | |
epithelial cell | 6 studies | 23% ± 8% | |
T cell | 6 studies | 51% ± 12% | |
erythrocyte | 6 studies | 40% ± 27% | |
CD8-positive, alpha-beta T cell | 6 studies | 52% ± 20% | |
natural killer cell | 6 studies | 51% ± 23% | |
B cell | 5 studies | 32% ± 9% | |
hematopoietic precursor cell | 5 studies | 34% ± 22% | |
transit amplifying cell | 5 studies | 34% ± 7% | |
pro-B cell | 5 studies | 40% ± 16% | |
endothelial cell | 4 studies | 19% ± 2% | |
progenitor cell | 4 studies | 32% ± 17% | |
erythroblast | 4 studies | 62% ± 18% | |
megakaryocyte-erythroid progenitor cell | 4 studies | 44% ± 24% | |
CD4-positive, alpha-beta T cell | 4 studies | 67% ± 7% | |
conventional dendritic cell | 3 studies | 23% ± 10% | |
abnormal cell | 3 studies | 24% ± 3% | |
neural crest cell | 3 studies | 43% ± 20% | |
plasma cell | 3 studies | 39% ± 14% | |
precursor B cell | 3 studies | 50% ± 22% | |
effector CD8-positive, alpha-beta T cell | 3 studies | 44% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 97% | 1285.66 | 1762 / 1809 | 96% | 17.54 | 454 / 472 |
esophagus | 92% | 336.42 | 1333 / 1445 | 99% | 15.72 | 182 / 183 |
ovary | 90% | 141.91 | 162 / 180 | 98% | 14.31 | 421 / 430 |
intestine | 87% | 345.39 | 839 / 966 | 97% | 14.00 | 510 / 527 |
kidney | 100% | 298.61 | 89 / 89 | 83% | 8.74 | 747 / 901 |
lung | 91% | 286.66 | 524 / 578 | 92% | 10.33 | 1063 / 1155 |
breast | 91% | 152.41 | 419 / 459 | 91% | 10.12 | 1012 / 1118 |
bladder | 90% | 175.10 | 19 / 21 | 91% | 13.30 | 460 / 504 |
stomach | 79% | 216.71 | 285 / 359 | 98% | 13.63 | 280 / 286 |
uterus | 81% | 132.28 | 138 / 170 | 95% | 18.21 | 435 / 459 |
thymus | 99% | 174.30 | 644 / 653 | 67% | 6.65 | 403 / 605 |
pancreas | 85% | 124.05 | 278 / 328 | 71% | 4.65 | 126 / 178 |
brain | 73% | 148.77 | 1932 / 2642 | 63% | 8.22 | 447 / 705 |
liver | 82% | 161.09 | 186 / 226 | 52% | 4.48 | 210 / 406 |
prostate | 99% | 226.07 | 243 / 245 | 34% | 1.56 | 172 / 502 |
adrenal gland | 92% | 172.34 | 237 / 258 | 37% | 2.33 | 85 / 230 |
spleen | 100% | 533.39 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.59 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 20.55 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 24.26 | 27 / 29 |
adipose | 84% | 144.25 | 1011 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 80% | 126.18 | 1064 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 72% | 1853.88 | 671 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 61% | 3.63 | 49 / 80 |
heart | 46% | 61.58 | 398 / 861 | 0% | 0 | 0 / 0 |
muscle | 3% | 2.65 | 24 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032259 | Biological process | methylation |
GO_0034097 | Biological process | response to cytokine |
GO_0033189 | Biological process | response to vitamin A |
GO_0045471 | Biological process | response to ethanol |
GO_0035999 | Biological process | tetrahydrofolate interconversion |
GO_0007623 | Biological process | circadian rhythm |
GO_0071897 | Biological process | DNA biosynthetic process |
GO_0051384 | Biological process | response to glucocorticoid |
GO_0097421 | Biological process | liver regeneration |
GO_0006231 | Biological process | dTMP biosynthetic process |
GO_0051593 | Biological process | response to folic acid |
GO_0019860 | Biological process | uracil metabolic process |
GO_0006235 | Biological process | dTTP biosynthetic process |
GO_0048589 | Biological process | developmental growth |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0009636 | Biological process | response to toxic substance |
GO_0060574 | Biological process | intestinal epithelial cell maturation |
GO_0051216 | Biological process | cartilage development |
GO_0032570 | Biological process | response to progesterone |
GO_0017148 | Biological process | negative regulation of translation |
GO_0046683 | Biological process | response to organophosphorus |
GO_0005739 | Cellular component | mitochondrion |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004799 | Molecular function | thymidylate synthase activity |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_1990825 | Molecular function | sequence-specific mRNA binding |
GO_0000900 | Molecular function | mRNA regulatory element binding translation repressor activity |
GO_0005542 | Molecular function | folic acid binding |
Gene name | TYMS |
Protein name | Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) Thymidylate synthase (EC 2.1.1.45) |
Synonyms | hCG_1994842 OK/SW-cl.29 TS |
Description | FUNCTION: Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway. . |
Accessions | ENST00000323250.9 [P04818-3] P04818 ENST00000323224.7 [P04818-2] ENST00000323274.15 [P04818-1] Q53Y97 |