CCNO report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CCNO at tissue level.

III. Associated gene sets

GO_0000079Biological processregulation of cyclin-dependent protein serine/threonine kinase activity
GO_0060271Biological processcilium assembly
GO_1903251Biological processmulti-ciliated epithelial cell differentiation
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0051301Biological processcell division
GO_0000278Biological processmitotic cell cycle
GO_0044772Biological processmitotic cell cycle phase transition
GO_0005730Cellular componentnucleolus
GO_0005813Cellular componentcentrosome
GO_0000307Cellular componentcyclin-dependent protein kinase holoenzyme complex
GO_0034451Cellular componentcentriolar satellite
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0016538Molecular functioncyclin-dependent protein serine/threonine kinase regulator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCCNO
Protein nameCyclin-O
Synonyms
DescriptionFUNCTION: Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking. .

AccessionsENST00000282572.5 [P22674-1]
P22674
ENST00000501463.2 [P22674-2]