Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 8 studies | 23% ± 11% | |
club cell | 5 studies | 26% ± 11% | |
respiratory goblet cell | 5 studies | 36% ± 11% | |
deuterosomal cell | 4 studies | 85% ± 7% |
Insufficient scRNA-seq data for expression of CCNO at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 1060.51 | 652 / 653 | 89% | 21.01 | 539 / 605 |
pancreas | 100% | 838.80 | 328 / 328 | 88% | 12.16 | 157 / 178 |
prostate | 89% | 423.84 | 217 / 245 | 84% | 15.76 | 424 / 502 |
stomach | 75% | 626.44 | 269 / 359 | 91% | 15.51 | 261 / 286 |
ovary | 63% | 110.58 | 114 / 180 | 86% | 24.36 | 370 / 430 |
bladder | 57% | 302.38 | 12 / 21 | 90% | 18.92 | 452 / 504 |
skin | 71% | 169.27 | 1286 / 1809 | 61% | 9.34 | 288 / 472 |
lung | 41% | 222.06 | 235 / 578 | 83% | 15.67 | 964 / 1155 |
esophagus | 29% | 49.91 | 422 / 1445 | 84% | 10.50 | 154 / 183 |
kidney | 73% | 196.33 | 65 / 89 | 39% | 5.06 | 350 / 901 |
uterus | 22% | 55.20 | 37 / 170 | 90% | 22.03 | 411 / 459 |
breast | 44% | 100.52 | 203 / 459 | 66% | 28.83 | 741 / 1118 |
intestine | 18% | 35.43 | 173 / 966 | 89% | 18.56 | 470 / 527 |
ureter | 0% | 0 | 0 / 0 | 100% | 56.21 | 1 / 1 |
brain | 78% | 323.32 | 2070 / 2642 | 20% | 2.49 | 140 / 705 |
tonsil | 0% | 0 | 0 / 0 | 89% | 13.53 | 40 / 45 |
adrenal gland | 19% | 24.93 | 48 / 258 | 64% | 12.90 | 147 / 230 |
blood vessel | 76% | 147.27 | 1015 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 63% | 9.99 | 50 / 80 |
liver | 10% | 12.62 | 22 / 226 | 28% | 2.99 | 112 / 406 |
lymph node | 0% | 0 | 0 / 0 | 14% | 1.40 | 4 / 29 |
adipose | 1% | 1.86 | 15 / 1204 | 0% | 0 | 0 / 0 |
heart | 0% | 0.33 | 3 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.98 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0000079 | Biological process | regulation of cyclin-dependent protein serine/threonine kinase activity |
GO_0060271 | Biological process | cilium assembly |
GO_1903251 | Biological process | multi-ciliated epithelial cell differentiation |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0051301 | Biological process | cell division |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0044772 | Biological process | mitotic cell cycle phase transition |
GO_0005730 | Cellular component | nucleolus |
GO_0005813 | Cellular component | centrosome |
GO_0000307 | Cellular component | cyclin-dependent protein kinase holoenzyme complex |
GO_0034451 | Cellular component | centriolar satellite |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0016538 | Molecular function | cyclin-dependent protein serine/threonine kinase regulator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CCNO |
Protein name | Cyclin-O |
Synonyms | |
Description | FUNCTION: Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation. Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking. . |
Accessions | ENST00000282572.5 [P22674-1] P22674 ENST00000501463.2 [P22674-2] |