Insufficient scRNA-seq data for expression of SRR at single-cell level.
Insufficient scRNA-seq data for expression of SRR at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 226.68 | 245 / 245 | 100% | 5.13 | 502 / 502 |
| brain | 100% | 304.80 | 2641 / 2642 | 100% | 14.80 | 705 / 705 |
| thymus | 100% | 198.42 | 653 / 653 | 100% | 5.17 | 604 / 605 |
| breast | 100% | 245.17 | 459 / 459 | 100% | 6.32 | 1115 / 1118 |
| esophagus | 100% | 244.66 | 1445 / 1445 | 99% | 3.30 | 182 / 183 |
| uterus | 100% | 240.52 | 170 / 170 | 99% | 4.42 | 453 / 459 |
| skin | 100% | 272.28 | 1808 / 1809 | 99% | 5.15 | 466 / 472 |
| pancreas | 100% | 158.49 | 327 / 328 | 99% | 3.18 | 176 / 178 |
| stomach | 100% | 175.27 | 358 / 359 | 98% | 3.12 | 281 / 286 |
| bladder | 100% | 232.52 | 21 / 21 | 98% | 3.28 | 493 / 504 |
| ovary | 99% | 201.64 | 179 / 180 | 98% | 3.53 | 422 / 430 |
| kidney | 100% | 160.69 | 89 / 89 | 97% | 4.09 | 878 / 901 |
| lung | 98% | 172.49 | 567 / 578 | 99% | 3.33 | 1146 / 1155 |
| intestine | 100% | 243.23 | 966 / 966 | 97% | 2.85 | 511 / 527 |
| adrenal gland | 100% | 311.81 | 258 / 258 | 96% | 3.33 | 220 / 230 |
| liver | 96% | 92.35 | 216 / 226 | 91% | 2.08 | 369 / 406 |
| adipose | 100% | 222.59 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 3.61 | 29 / 29 |
| spleen | 100% | 169.88 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 3.77 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.81 | 1 / 1 |
| muscle | 100% | 183.43 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 180.36 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 96% | 3.86 | 77 / 80 |
| heart | 95% | 150.81 | 819 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 46% | 109.72 | 430 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0070179 | Biological process | D-serine biosynthetic process |
| GO_0014070 | Biological process | response to organic cyclic compound |
| GO_0042866 | Biological process | pyruvate biosynthetic process |
| GO_0070178 | Biological process | D-serine metabolic process |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0009069 | Biological process | serine family amino acid metabolic process |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0006563 | Biological process | L-serine metabolic process |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0045177 | Cellular component | apical part of cell |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0030170 | Molecular function | pyridoxal phosphate binding |
| GO_0030378 | Molecular function | serine racemase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0000287 | Molecular function | magnesium ion binding |
| GO_0003941 | Molecular function | L-serine ammonia-lyase activity |
| GO_0008721 | Molecular function | D-serine ammonia-lyase activity |
| GO_0030165 | Molecular function | PDZ domain binding |
| GO_0018114 | Molecular function | threonine racemase activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0016594 | Molecular function | glycine binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SRR |
| Protein name | L-serine ammonia-lyase (EC 4.3.1.17) Serine racemase Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. . |
| Accessions | ENST00000576848.1 I3L4W4 ENST00000570662.2 ENST00000572709.5 Q3ZK31 ENST00000574229.1 ENST00000576620.5 ENST00000344595.10 V9GYE8 I3L4L3 ENST00000574987.1 I3L3N0 ENST00000575840.5 I3L4B4 Q9GZT4 |