Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type B pancreatic cell | 4 studies | 53% ± 21% | |
| glutamatergic neuron | 4 studies | 28% ± 11% | |
| pancreatic D cell | 3 studies | 60% ± 25% | |
| rod bipolar cell | 3 studies | 23% ± 1% | |
| enteroendocrine cell | 3 studies | 30% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreas | 3 studies | 26% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 93% | 505.26 | 306 / 328 | 80% | 27.05 | 143 / 178 |
| brain | 71% | 1512.05 | 1869 / 2642 | 86% | 13.46 | 605 / 705 |
| adrenal gland | 37% | 232.47 | 95 / 258 | 76% | 90.43 | 175 / 230 |
| intestine | 53% | 142.19 | 515 / 966 | 53% | 17.15 | 280 / 527 |
| skin | 41% | 148.38 | 737 / 1809 | 45% | 10.25 | 212 / 472 |
| breast | 58% | 353.64 | 268 / 459 | 24% | 43.48 | 264 / 1118 |
| stomach | 36% | 102.01 | 129 / 359 | 41% | 10.44 | 117 / 286 |
| blood vessel | 73% | 548.13 | 975 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 67% | 526.83 | 438 / 653 | 5% | 0.18 | 33 / 605 |
| bladder | 33% | 265.62 | 7 / 21 | 31% | 8.88 | 154 / 504 |
| esophagus | 15% | 47.16 | 223 / 1445 | 45% | 4.72 | 82 / 183 |
| lung | 19% | 46.85 | 108 / 578 | 36% | 15.76 | 411 / 1155 |
| adipose | 53% | 315.31 | 641 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 13% | 46.01 | 22 / 170 | 33% | 3.72 | 153 / 459 |
| eye | 0% | 0 | 0 / 0 | 38% | 1.66 | 30 / 80 |
| ovary | 22% | 72.39 | 40 / 180 | 13% | 0.54 | 56 / 430 |
| kidney | 15% | 31.89 | 13 / 89 | 11% | 0.79 | 102 / 901 |
| heart | 26% | 81.46 | 221 / 861 | 0% | 0 | 0 / 0 |
| prostate | 17% | 75.66 | 42 / 245 | 4% | 0.34 | 21 / 502 |
| tonsil | 0% | 0 | 0 / 0 | 11% | 0.16 | 5 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.31 | 3 / 29 |
| muscle | 10% | 36.05 | 81 / 803 | 0% | 0 | 0 / 0 |
| liver | 0% | 1.15 | 1 / 226 | 5% | 5.24 | 19 / 406 |
| spleen | 1% | 0.89 | 2 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0010157 | Biological process | response to chlorate |
| GO_0043434 | Biological process | response to peptide hormone |
| GO_0031016 | Biological process | pancreas development |
| GO_0070542 | Biological process | response to fatty acid |
| GO_0009749 | Biological process | response to glucose |
| GO_0016486 | Biological process | peptide hormone processing |
| GO_0016540 | Biological process | protein autoprocessing |
| GO_0048678 | Biological process | response to axon injury |
| GO_0043043 | Biological process | peptide biosynthetic process |
| GO_0070555 | Biological process | response to interleukin-1 |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0050714 | Biological process | positive regulation of protein secretion |
| GO_0031667 | Biological process | response to nutrient levels |
| GO_0022008 | Biological process | neurogenesis |
| GO_0051384 | Biological process | response to glucocorticoid |
| GO_0006508 | Biological process | proteolysis |
| GO_0021983 | Biological process | pituitary gland development |
| GO_0009410 | Biological process | response to xenobiotic stimulus |
| GO_0030070 | Biological process | insulin processing |
| GO_0051592 | Biological process | response to calcium ion |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0005615 | Cellular component | extracellular space |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0043204 | Cellular component | perikaryon |
| GO_0043679 | Cellular component | axon terminus |
| GO_0043005 | Cellular component | neuron projection |
| GO_0034774 | Cellular component | secretory granule lumen |
| GO_0030425 | Cellular component | dendrite |
| GO_0005802 | Cellular component | trans-Golgi network |
| GO_0030133 | Cellular component | transport vesicle |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | PCSK1 |
| Protein name | Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) (PC1) Proprotein convertase subtilisin/kexin type 1 Neuroendocrine convertase 1 (EC 3.4.21.93) (Prohormone convertase 1) (Proprotein convertase 1) |
| Synonyms | NEC1 |
| Description | FUNCTION: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP. . FUNCTION: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP. . |
| Accessions | P29120 ENST00000509190.1 ENST00000311106.8 [P29120-1] A1L3V6 ENST00000508626.5 [P29120-2] D6RJA3 |
