CPB2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010757Biological processnegative regulation of plasminogen activation
GO_0003331Biological processpositive regulation of extracellular matrix constituent secretion
GO_0071333Biological processcellular response to glucose stimulus
GO_0009410Biological processresponse to xenobiotic stimulus
GO_0097421Biological processliver regeneration
GO_0007596Biological processblood coagulation
GO_0006508Biological processproteolysis
GO_2000346Biological processnegative regulation of hepatocyte proliferation
GO_0042730Biological processfibrinolysis
GO_0030163Biological processprotein catabolic process
GO_0051918Biological processnegative regulation of fibrinolysis
GO_0005615Cellular componentextracellular space
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0008270Molecular functionzinc ion binding
GO_0004181Molecular functionmetallocarboxypeptidase activity

IV. Literature review

[source]
Gene nameCPB2
Protein nameCarboxypeptidase B2 (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Plasma carboxypeptidase B) (pCPB) (Thrombin-activable fibrinolysis inhibitor) (TAFI)
Carboxypeptidase B2
Synonyms
DescriptionFUNCTION: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. .

AccessionsENST00000675730.1
ENST00000181383.10 [Q96IY4-1]
A0A6Q8PG06
ENST00000674625.1
A0A087WSY5
A0A6Q8PHS9
ENST00000439329.5
Q96IY4